Q1290. 40-year-old man sustains a head injury involving the left temporal region following a road traffic accident. After regaining consciousness, he speaks fluently but his speech is irrelevant and meaningless. He is unable to comprehend spoken language. Which cortical area is most likely affected?

Q1291. A patient with cavernous sinus infection presents with ophthalmoplegia and loss of sensation over the forehead, cheek, and upper lip, while sensation over the lower lip is preserved. Which of the following cranial nerves will be spared in this condition?

Q1294. Upper GI endoscopy reveals a perforated bleeding ulcer on the posterior wall of the first part of the duodenum. Which artery is most likely to be involved? Image

Q1295. The ansa cervicalis supplies motor innervation to all of the following muscles EXCEPT:

Q1301. A scientist was performing an experiment on a nerve. H53e applies a stimulus during the refractory period. The nerve fails to excite because:

Q1302. Strength Duration Curve At , which point aortic valve opens ?

Q1303. In the following pressure-volume curve of the bladder, what is the physiological basis for the segment labeled Ib?

Q1305. A patient undergoes a surgery where one lung is removed due to malignancy. Which of the following parameters should be measured to accurately assess the remaining lung's elasticity, independent of the change in lung volume?

Q1308. and buttocks. Laboratory evaluation reveals markedly elevated serum triglyceride levels with a predominance of chylomicrons even in the fasting state. There is no significant elevation of LDL cholesterol. Which of the following defects is the most likely underlying cause of this condition?

Q1309. A patient presents with joint pain and hepatomegaly. Histopathological examination reveals abnormal deposition of glycolipids and glycoconjugates. What is the most likely subcellular organelle involved in this deposition?

Q1310. A 9-month-old child presents to the pediatric OPD with anemia, failure to thrive, and hepatomegaly. Histopathological examination shows macrophages with a “crumpled tissue paper–like” cytoplasm due to cerebroside accumulation. What is the most likely diagnosis?

Q1311. A patient presents with retinitis pigmentosa, ataxia, ichthyosis, and cardiac conduction defects. Laboratory results show increased peroxisomal deposition of phytanic acid. What is the most likely diagnosis?

Q1312. A young boy is brought to the pediatric clinic with developmental delay, dystonia, hyperuricemia, and a striking history of self-mutilating behavior such as biting of lips and fingers. There is also a family history of a similar illness in male relatives. Which of the following enzymes is defective in this disorder?

Q1313. A child presents to pediatric OPD with hepatosplenomegaly. On examination histopathological examination shows foam cells in bone marrow due to lipid accumulation. What is the most likely diagnosis?

Q1314. A newborn infant develops vomiting, jaundice, and failure to thrive. On labs UPG Ill to CPG conversion is affected. Which of the following enzyme is likley defective?

Q1315. A 4-month-old infant is brought with poor feeding, failure to thrive, and progressive hypotonia. On examination, the baby has macroglossia and signs of cardiomegaly. Echocardiography reveals hypertrophic cardiomyopathy. Laboratory evaluation shows deficiency of acid maltase. What is the most likely diagnosis?

Q1316. severe sepsis. He presents with acute onset dyspnea, hypoxemia refractory to oxygen therapy, and difuse bilateral infiltrates on chest X-ray. Which of the following components of pulmonary surfactant is primarily deficient or inactivated in this condition?

Q1317. receptors. The hormone–receptor complex then translocates to the nucleus and binds to specific DNA sequences to regulate gene transcription. Which of the following DNA- binding motifs enables steroid hormone receptors to attach to their target sites on DNA?

Q1318. of life. Laboratory investigations reveal severe hyperammonemia, low citrulline levels, elevated plasma glutamine, and normal orotic acid levels in urine. There is no evidence of metabolic acidosis or hypoglycemia. What is the most likely diagnosis?