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Questions from standard medical textbooks with detailed explanations

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BiochemistryNucleic Acids
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Q51960. Inducers and repressors are

A.Enhancer and silencer elements respectively
B.Trans-acting factors
C.Cis-acting elements
D.Regulatory proteins

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51961. cis-acting elements include

A.Steroid hormones
B.Calcitriol
C.Histones
D.Silencers

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51962. Silencer elements

A.Are trans-acting factors
B.Are present between promoters and the
C.Decrease the expression of some structural
D.Encode specific repressor proteins

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51963. trans-acting factors include

A.Promoters
B.Repressors
C.Enhancers
D.Silencers

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51964. Enhancer elements have all the following features except

A.They increase gene expression through a
B.Each enhancer activates a specific promoter
C.They may be located far away from the
D.They may be upstream or downstream from

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51965. Amplification of dihydrofolate reductase gene may be brought about by

A.High concentrations of folic acid
B.Deficiency of folic acid
C.Low concentration of thymidylate
D.Amethopterin

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51966. Proteins which interact with DNA and affect the rate of transcription possess the following structural motif:

A.Helix-turn-helix motif
B.Zinc finger motif
C.Leucine zipper motif
D.All of these

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51967. Lac operon is a cluster of genes present in

A.Human beings
B.E. coli
C.Lambda phage
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51968. Lac operon is a cluster of

A.Three structural genes
B.Three structural genes and their promoter
C.A regulatory gene, an operator and a
D.A regulatory gene, an operator, a promoter

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51969. The regulatory i gene of lac operon

A.Is inhibited by lacotse
B.Is inhibited by its own product, the repressor
C.Forms a regulatory protein which increases
D.Is constitutively expressed

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51970. RNA polymerase holoenzyme binds to lac operon at the following site:

A.i gene
B.z gene
C.Operator locus
D.Promoter region

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51971. Trancription of z, y and a genes of lac operon is prevented by

A.Lactose
B.Allo-lactose
C.Repressor
D.cAMP

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51972. Transcription of structural genes of lac operon is prevented by binding of the repressor tetramer to

A.i gene
B.Operator locus
C.Promoter
D.z gene

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51973. The enzymes encoded by z, y and a genes of lac operon are inducible, and their inducer is

A.Lactose
B.Allo-lactose
C.Catabolite gene activator protein
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51974. Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by

A.Catabolite gene activator protein (CAP)
B.cAMP
C.CAP-cAMP complex
D.None of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51975. Lactose or its analogues act as positive regulators of lac operon by

A.Attaching to i gene and preventing its
B.Increasing the synthesis of catabolite gene
C.Attaching to promoter region and facilitating
D.Binding to repressor subunits so that the

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51976. Expression of structural genes of lac operon is affected by all the following except

A.Lactose or its analogues
B.Repressor tetramer
C.cAMP
D.CAP-cAMP complex

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51977. The coding sequences in lac operon include

A.i gene
B.i gene, operator locus and promoter
C.z, y and a genes
D.i, z, y and a genes

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51978. Mutations can be caused by

A.Ultraviolet radiation
B.Ionising radiation
C.Alkylating agents
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51979. Mutations can be caused by

A.Nitrosamine
B.Dimethyl sulphate
C.Acridine
D.All of these

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MCQs in BiochemistryNucleic Acids
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