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BiochemistryNucleic Acids
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Q51940. In eukaryotes, the 40 S pre-initiation complex contains all the following initiation factors except

A.eIF-1A
B.eIF-2
C.eIF-3
D.eIF-4

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51941. Eukaryotic initiation factors 4A, 4B and 4F bind to

A.40 S ribosomal subunit
B.60 S ribosomal subunit
C.mRNA
D.Amino acyl tRNA

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51942. The codon which serves as translation start signal is

A.AUG
B.UAG
C.UGA
D.UAA

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51943. The first amino acyl tRNA approaches 40 S ribosomal subunit in association with

A.eIF-1A and GTP
B.eIF-2 and GTP
C.eIF-2C and GTP
D.eIF-3 and GTP

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51944. eIF-1A and eIF-3 are required

A.For binding of amino acyl tRNA to 40 S
B.For binding of mRNA to 40 S ribosomal
C.For binding of 60 S subunit to 40 S subunit
D.To prevent binding of 60 S subunit to 40 S

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51945. eIF-4 A possesses

A.ATPase activity
B.GTPase activity
C.Helicase activity
D.None of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51946. eIF-4 B

A.Binds to 3’ chain initiation codon on mRNA
B.Binds to 3’ end of mRNA
C.Binds to 5’ end of mRNA
D.Unwinds mRNA near its 5’ end

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51947. Peptidyl transferase activity is present in

A.40 S ribosomal subunit
B.60 S ribosomal subunit
C.eEF-2
D.Amino acyl tRNA

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51948. After formation of a peptide bond, mRNA is translocated along the ribosome by

A.eEF-1 and GTP
B.eEF-2 and GTP
C.Peptidyl transferase and GTP
D.Peptidyl transferase and ATP

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51949. Binding of formylmehtionyl tRNA to 30 S ribosomal subunit of prokaryotes is inhibited by

A.Streptomycin
B.Chloramphenicol
C.Erythromycin
D.Mitomycin

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51950. Tetracyclines inhibit binding of amino acyl tRNAs to

A.30 S ribosomal subunits
B.40 S ribosomal subunits
C.50 S ribosomal subunits
D.60 S ribosomal subunits

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51951. Peptidyl transferase activity of 50 S ribosomal subunits is inhibited by

A.Rifampicin
B.Cycloheximide
C.Chloramphenicol (D) Erythromycin

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51952. Erythromycin binds to 50 S ribosomal sub unit and

A.Inhibits binding of amino acyl tRNA
B.Inhibits Peptidyl transferase activity
C.Inhibits translocation
D.Causes premature chain termination

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51953. Puromycin causes premature chain termination in

A.Prokaryotes
B.Eukaryotes
C.Both (A) and (B)
D.None of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51954. Diphtheria toxin inhibits

A.Prokaryotic EF-1
B.Prokaryotic EF-2
C.Eukaryotic EF-1
D.Eukaryotic EF-2

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51955. The proteins destined to be transported out of the cell have all the following features except

A.They possess a signal sequence
B.Ribosomes synthesizing them are bound to
C.After synthesis, they are delivered into Golgi
D.They are tagged with ubiquitin

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51956. SRP receptors involved in protein export are present on

A.Ribosomes
B.Endoplasmic reticulum
C.Golgi appartus
D.Cell membrane

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51957. The signal sequence of proteins is cleaved off

A.On the ribosomes immediately after synthesis
B.In the endoplasmic reticulum
C.During processing in Golgi apparatus
D.During passage through the cell membrane

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51958. The half-life of a protein depends upon its

A.Signal sequence
B.N-terminus amino acid
C.C-terminus amino acid
D.Prosthetic group

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51959. Besides structural genes that encode proteins, DNA contains some regulatory sequences which are known as

A.Operons
B.Cistrons
C.Cis-acting elements (D) Trans-acting factors

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MCQs in BiochemistryNucleic Acids
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