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Questions from standard medical textbooks with detailed explanations

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BiochemistryNucleic Acids
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Q51980. Nitrosamine can deaminate

A.Cytosine to form uracil
B.Adenine to form xanthine
C.Guanine to form hypoxanthine
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51981. Exposure of DNA to ultraviolet radiation can lead to the formation of

A.Adenine dimers
B.Guanine dimers
C.Thymine dimers
D.Uracil dimers

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51982. Damage to DNA caused by ultraviolet radiation can be repaired by

A.uvr ABC excinuclease
B.DNA polymerase I
C.DNA ligase
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51983. Xeroderma pigmentosum results from a defect in

A.uvr ABC excinuclease
B.DNA polymerase I
C.DNA ligase
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51984. All the following statements about xeroderma pigmentosum are true except

A.It is a genetic disease
B.Its inheritance is autosomal dominant
C.uvr ABC excinuclease is defective in this
D.It results in multiple skin cancers

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51985. Substitution of an adenine base by guanine in DNA is known as

A.Transposition
B.Transition
C.Transversion
D.Frameshift mutation

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51986. Substitution of a thymine base by adenine in DNA is known as ((A) Transposition

A.Transition
B.Transversion
C.Frameshift mutation

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51987. A point mutation results from

A.Substitution of a base
B.Insertion of a base
C.Deletion of a base
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51988. Substitution of a base can result in a

A.Silent mutation
B.Mis-sense mutation
C.Nonsense mutation(D) All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51989. A silent mutation is most likely to result from

A.Substitution of the first base of a codon
B.Substitution of the third base of a codon
C.Conversion of a nonsense codon into a sense
D.Conversion of a sense codon into a nonsense

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51990. The effect of a mis-sense mutation can be

A.Acceptable
B.Partially acceptable
C.Unacceptable
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51991. Amino acid sequence of the encoded protein is not changed in

A.Silent mutation
B.Acceptable mis-sense mutation
C.Both (A) and (B)
D.None of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51992. Haemoglobin S is an example of a/an

A.Silent mutation
B.Acceptable mis-sense mutation
C.Unacceptable mis-sense mutation
D.Partially acceptable mis-sense mutation

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51993. If the codon UAC on mRNA changes into UAG as a result of a base substitution in DNA, it will result in

A.Silent mutation
B.Acceptable mis-sense mutation
C.Nonsense mutation
D.Frameshift mutation

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51994. Insertion of a base in a gene can cause

A.Change in reading frame
B.Garbled amino acid sequence in the
C.Premature termination of translation
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51995. A frameshift mutation changes the reading frame because the genetic code

A.Is degenerate
B.Is overlapping
C.Has no punctuations
D.Is universal

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51996. Suppressor mutations occur in

A.Structural genes
B.Promoter regions
C.Silencer elements (D) Anticodons of tRNA

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51997. Suppressor tRNAs can neutralize the effects of mutations in

A.Structural genes
B.Promoter regions
C.Enhancer elements(D) All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51998. Mutations in promoter regions of genes can cause

A.Premature termination of translation
B.Change in reading frame of downstream
C.Decreased efficiency of transcription
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51999. Mitochondrial protein synthesis is inhibited by

A.Cycloheximide
B.Chloramphenicol
C.Diptheria toxin
D.None of these

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MCQs in BiochemistryNucleic Acids
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