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PharmacologyDrugs Acting On Autonomous Nervous System
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Q55694.Β If a patient gives history of urticaria, itching and swelling of lips following injection of penicillin G, then

A.He will develop similar reaction whenever
B.He can be given ampicillin safely
C.He can be given oral phenoxymethyl
D.All natural and semisynthetic penicillins are

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Q55695.Β The most important reason for highly restricted use of penicillin G injections in present day therapeutics is its

A.Narrow spectrum of activity
B.Potential to cause hypersensitivity reaction
C.Short duration of action
D.Neurotoxicity

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Q55696.Β Benzathine penicillin injected once every 4 weeks for 5 years or more is the drug of choice for

A.Agranulocytosis patients
B.Prophylaxis of bacterial endocarditis in
C.Prophylaxis of rheumatic fever
D.Treatment of anthrax

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Q55697.Β Which of the following is not a semisyn- thetic penicillin ?

A.Procaine penicillin(b) Ampicillin
B.Cloxacillin
C.Carbenicillin

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Q55698.Β Cloxacillin is indicated in infections caused by the following organism(s)

A.Staphylococci
B.Streptococci
C.Gonococci
D.All of the above

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Q55699.Β The most frequent side effect of oral ampicillin is

A.Nausea and vomiting
B.Loose motions
C.Constipation
D.Urticaria

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Q55700.Β Amoxicillin is inferior to ampicillin for the treatment of the following infection

A.Typhoid
B.Shigella enteritis
C.Subacute bacterial endocarditis
D.Gonorrhoea

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Q55701.Β Piperacillin differs from carbenicillin in the following respect(s)

A.It is more active against pseudomonas
B.It is active against Klebsiella also
C.It is acid resistant
D.Both (a) and (b)

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Q55702.Β Clavulanic acid is combined with amoxicillin because

A.It kills bacteria that are not killed by-moxicillin
B.It reduces renal clearance of amoxicillin
C.It counteracts the adverse effects of
D.It inhibits beta lactamases that destroy

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Q55703.Β Amoxicillin + Clavulanic acid is active against the following organism except

A.Methicillin resistant Staph. aureus
B.Penicillinase producing Staph. aureus
C.Penicillinase producing n. gonorrhoeae
D.Ξ²-lactamase producing E. coli

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Q55704.Β A woman’s neglected hangnail has developed into a mild staphylococcal cellulites. Which of the following regimens would be appropriate oral therapy?

A.Dicloxacillin 125 mg q6h
B.Vancomycin 250 mg q6h
C.Methicillin 500 mg q6h
D.Cefazolin 1 g q8h

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Q55705.Β Cefotaxime has the following properties except

A.It is highly active against aerobic gram
B.It is the most active cephalosporin against
C.It produces an active metabolite
D.It has achieved high cure rates in serious

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Q55706.Β Select the fourth generation cephalospor- in among the following

A.Cefpirome
B.Ceftizoxime
C.Ceftazidime
D.Cefuroxime

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Q55707.Β The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is

A.They chelate Ca2+ ions and alter permeability
B.They bind to 30S ribosomes and inhibit
C.They bind to 50S ribosomes and interfere
D.They interfere with DNA mediated RNA

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Q55708.Β Select the most potent tetracycline antibiotic

A.Demeclocycline
B.Methacycline
C.Minocycline
D.Doxycycline

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Q55709.Β An 8-year-old child presented with brownish discoloured and deformed anterior teeth. History of having received an antibiotic about 4 years earlier was obtained. Which antibiotic could be responsible for the condition ?

A.Chloramphenicol (b) Tetracycline
B.Erythromycin
C.Genetamicin

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Q55710.Β The most suitable tetracycline for use in a patient with impaired renal function is

A.Chlortetracycline (b) Demeclocycline
B.oxytetracycine
C.Doxycycline

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Q55711.Β Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because

A.It is completely absorbed in the small
B.It is inactivated by the gut microflora
C.It is not active against the microbes of the
D.It is a potent tetracycline and inhibits the

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Q55712.Β Tetracyclines are still the first choice drugs for the following disease.

A.Granuloma linguinale
B.Chancroid
C.Syphilis
D.Gonorrhoea in patients allergic to penicillin

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Q55713.Β Chloramphenicol is more active than tetracyclines against

A.Bateroides fragilis
B.Treponema pallidum
C.Streptococci
D.Staphylococci

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