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PharmacologyDrugs Acting On Autonomous Nervous System
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Q55674. A man has an Escherichia coli bacteremia with a low-grade fever (101.6°F). Appropriate management of his fever would be

A.Give acetaminophen 650 mg orally every 4
B.Give aspirin 650 mg orally every 4 hours
C.Give alternating doses of aspirin and
D.Withhold antipyretics, and use the fever curve

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Q55675. Superinfections are more common with

A.Use of narrow spectrum antibiotics
B.Short courses of antibiotics
C.Use of antibiotics that are completely absorbed
D.Use of antibiotic combinations covering both

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Q55676. Select the antibiotic whose dose must be reduced in patients with renal insufficiency

A.Ampicillin
B.Chloramphenicol
C.Tobramycin
D.Erythromycin

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Q55677. Which antimicrobial should be avoided in patients of liver disease ?

A.Chlortetracycline
B.Cotrimoxazole
C.Cephalexin
D.Ethambutol

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Q55678. What is break point concentration of an antibiotic ?

A.Concentration at which the antibiotic lyses the
B.Concentration of the antibiotic which demarks
C.Concentration of the antibiotic which
D.Concentration at which a bacteriostatic antibiotic

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Q55679. Which type of antimicrobial drug combination is most likely to exhibit antagonism ?

A.Bactericidal + Bactericidal
B.Bactericidal + Bacteriostatic for a highly
C.Bactericidal + Bacteriostatic for a marginally
D.Bacteriostatic + Bacteriostatic

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Q55680. Indicate the sulfonamide whose sodium salt yields a nearly neutral solution which is suitable for topical use in the eye

A.Sulfadiazine
B.Sulfacetamide
C.Sulfamerazine
D.Sulfamethizole

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Q55681. Sulfamethoxypyridazine and other related long acting sulfonamides have now gone into disuse because

A.They have produced serious cutaneous
B.They have produced high incidence of
C.They interact with many drugs
D.They do not penetrate blood-brain barrier

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Q55682. Which of the following is not true of sulfonamides ?

A.They are primarily metabolized by acetylation
B.They are more likely to produce crystalluria
C.They may exert bactericidal action in the
D.Used alone, they have become therapeutically

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Q55683. Adverse effects of ciprofloxacin are referable primarily to the following except

A.Gastrointestinal tract
B.Kidney
C.Skin
D.Nervous system

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Q55684. A single oral dose of the following drug can cure most cases of uncomplicated gonorrhoea

A.Ciprofloxacin
B.Cotrimoxazole
C.Spectinomycin
D.Doxycycline

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Q55685. Which fluoroquinolone has markedly enhanced activity against gram positive bacteria and anaerobes ?

A.Pefloxacin
B.Ciprofloxacin
C.Sparfloxacin
D.Norfloxacin

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Q55686. A woman has an upper respiratory in- fection. Six years ago, she experienced an episode of bronchospasm follwing penicillin V therapy. The cultures now reveal a strain of streptococcus pneumo- niae that is sensitive to all of the follow- ing drugs. Which of these drugs would be the best choice for this patient?

A.Amoxicillin/clavulanate
B.Erythromycin
C.Ampicillin
D.cefaclor

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Q55687. Important microbiological features of ciprofloxacin include the following except

A.Long postantibiotic effect
B.Marked suppression of intestinal anaerobes
C.MBC values close to MIC values
D.Slow development of resistance

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Q55688. Currently the drug of choice for emperic treatment of typhoid fever is

A.Chloramphenicol (b) Cotrimoxaxole
B.Ciprofloxacin
C.Ampicillin

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Q55689. In the treatment of typhoid fever, ciprof- loxacin has the following advantage(s)

A.It is effective in nearly all cases
B.Early abetment of fever and other symptoms
C.Development of carrier state is less likely
D.All of the above

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Q55690. Penicillins interfere with bacterial cell wall synthesis by

A.Inhibiting synthesis of N-acetyl muramic acid
B.Inhibiting conjugation between N-acetyl
C.Inhibiting transpeptidases and carboxy
D.Counterfeiting for D-alanine in the bacterial

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Q55691. All of the following drugs are suitable oral therapy for a lower urinary tract infection due to Pseudomonas aeruginosa except

A.Norfloxacin
B.Trimethoprim-sulfamethxazole
C.Ciprofloxacin
D.Carbenicillin

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Q55692. Gram negative organisms are largely insensitive to benzyl penicillin because

A.They produce large quantities of penicillinase
B.They do not utilize D-alanine whose
C.Benzyl penicillin is not able to penetrate
D.Both (a) and (b)

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Q55693. The penicillin G preparation with the longest duration of action is

A.Benzathine penicillin
B.Sodium penicillin
C.Potassium penicillin
D.Procaine penicillin

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