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PharmacologyDrugs Acting On Autonomous Nervous System
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Q55614. Chronic use of nitrites may lead to

A.Allergic response
B.Addietion
C.Atherosclerotic changes
D.Tolerance

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Q55615. While treating auricular fibrillation, digi- talization is necessary prior to quinidine because

A.It prevents paradoxical increase in ventricular
B.Quinidine is only effective in the presence
C.It reduces the dose and side effects of
D.It antagonizes the extracardiac effects of

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Q55616. Which of the following pharmacological properties of quinidine is not useful clinically?

A.Shorterning of A-V nodal refractory period
B.Depression of cardiac contractility
C.Decrease in the automaticity of the normal
D.Reduction in the slope of slow diastolic

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Q55617. Resperine is used in hypertension, only in low doses because

A.It is a very strong antihypertensive
B.Side effects become disproportionately
C.High doses on chronic use cause addiction
D.It has a very long duration of action

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Q55618. There is no rationale of giving digitoxin parenterally because

A.It is very painful if given parenterally
B.Its total initial oral and parenteral digitalization
C.It is quickly metabolized if given I.V. or I.M.
D.It is always preferred by I.V. route

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Q55619. For a longer duration of action nitroglycerine can be administered by which of the following routes

A.Sublingual
B.Inhalation
C.Intravenous
D.Cutaneous application

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Q55620. Activation of prothrombin to thrombin is carried out by

A.Factor VIII
B.Factor V
C.Factor IX
D.All of the above

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Q55621. Which of the following is not a calcium channel blocker?

A.Verapamil
B.Diltiazam
C.Prenylamine
D.Propranolol

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Q55622. In the treatment of cardiac shock, the drug of choice is

A.Dopamine
B.Propranolol
C.Phenoxybenzamine
D.Metaraminol

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Q55623. Polymorphic ventricular tachycardia can be a complication of

A.Loratadine
B.Cetirizine
C.Astemizole
D.C + D

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Q55624. In hypertension which drug besides lowering blood pressure arrests and even reverses cardiac hypertrophy MCQs IN PHARMACOLOGY 132

A.ACE inhibitors
B.Betablockers
C.Calcium channel blockers
D.Diuretics

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Q55625. The ACE inhibitor useful in hypertensive emergencies is

A.Enalaprilat
B.Benzalaprilat
C.Fosinoprilat
D.Quinoprilat

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Q55626. Effect of decreased vitamin K on action of warfarin is

A.Enhanced anticoagulatory effect
B.Decreased anticoagulatory
C.No effect
D.Unpredictable effect

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Q55627. Nitroglycerin ointment in clinical use is

A.1%
B.2%
C.5%
D.10%

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Q55628. Which of the following is directly acting vascular smooth muscle relaxant ?

A.Verapamil
B.Minoxidil
C.Clonidine
D.Diazoxide

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Q55629. The most potent stimulant for heart is

A.Adrenaline
B.Noradrenaline
C.Dopamine
D.Ephedrine

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Q55630. Fibrinolysis is mainly carried out by

A.Tissue – type plasminogen activator
B.Urokinase – type plasminogen activator
C.Both (a) and (b)
D.None of the above

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Q55631. Following is a phenothiazine analog with sodium channel blocking properties

A.Moricizine
B.Mexiletine
C.Tocainide
D.Propafenone

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Q55632. Isoniazid is a primary antitubercular agent that

A.Requires pyridoxine supplementation
B.May discolor the tears, saliva, urine or feces
C.Causes ocular complications that are
D.May be ototoxic and nephrotoxic

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Q55633. A 36-year-old woman recently treated for leukemia is admitted to hospital with malaise, chills and high fever. Gram stain of blood reveals the presence of gram- negative bacilli. The initial diagnosis is bacteremia and parenteral antibiotics are indicated. The records of the patient reveal that she had a severe uriticarial risk, hypotension, and respiratory difficulty following oral penicillin V about 6 months ago. The most appropriate drug regimen for empiric treatment is

A.Ampicillin plus sulbactam
B.Aztreonam
C.Cefazolin
D.Imipenem plus cilastatin

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