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Q55594.ย After oral administration peak concentra- tion of digoxin is reached in
A. 1 to 2 mins
B. 30 to 60 mins
C. 5 to 10 mins
D. 4 to 6 hours
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Q55595.ย The normal therapeutic plasma con- centration of digitalis is
A. 0.5 to 1.5 ng/ml and toxicity appears above
B. 1 to 5 ng/ยตl and toxicity appears above 50
C. 0.1 to 0.5 ฮฑg mg/ml and toxicity appears
D. 0.5 to 1.5 ฮฑg mg/ml and toxicity appears
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Q55596.ย Drug of choice for digitalis induced arrhythmia is
A. Propranolol
B. Phenytoin
C. Xylocaine
D. Phenylephrine
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Q55597.ย In which of the following conditions, digitalis is most likely to be beneficial?
A. Heart failure from valvular lesions
B. Furosemide
C. Heart disease with anaemia
D. Heart failure from thyrotoxicosis
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Q55598.ย Nicotinic acid
A. Decreases production of VLDL
B. Decreases LDL levels
C. Increases HDL levels
D. All of the above
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Q55599.ย Which of the following would least likely benefit a patient in acute pulmonary edema due to congestive heart failure?
A. Intravenous morphine
B. Digoxin
C. Oxygen
D. Rotating tourniquets
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Q55600.ย Monoamine oxidase inhibitors
A. Do not cause postural hypotension
B. Are known to reduce blood pressure by
C. Have a prompt hypotensive action
D. Generally do not cause tachycardia
Pharmacology Drugs Acting On Autonomous Nervous System
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Q55601.ย Digitalis is given before quinidine in the treatment of atrial fibrillation, because digitalis increase A-V conduction and counteracts
A. The โVagotonicโ effect of quinidine and
B. The โVagolyticโ effect of quinidine and
C. The โVagotonicโ effect of quinidine and
D. The โVagolyticโ effect of quinidine and
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Q55602.ย The earliest toxic symptom of chronic digitalis administration is
A. Altered color vision
B. Psychic symptoms
C. Anorexia, nausea, vomiting
D. Retrosternal pain
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Q55603.ย In normal condition sequence of con- duction of cardiac action potential is
A. SA node to AV node to bundle of His to atrium
B. SA node to atrium to AV node to bundle of
C. SA node to atrium to bundle of His to AV
D. SA node to AV node to atrium to bundle of
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Q55604.ย While treating a CHF patient with cardiac glycoside, one notices that the patientโs resting heart rate, which previously had been 86/min is now 40/min. This would
A. Probably be unrelated to drug administration
B. Be the desired response of the drug
C. Probably be the result of drug-induced heart
D. Be an indication for increasing the drug dose.
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Q55605.ย Digoxin differs from digitoxin in that digoxin
A. Has a longer half life
B. Is completely absorbed from the GI tract
C. Is bound extensively to plasma proteins
D. Its half-life is more dependent on the
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Q55606.ย Diazoxide is administered by slow IV- injection in emergency treatment of hypertension because
A. The drug is rapidly biotransformed by hepatic
B. The drug is highly lipid-soluble and quickly
C. This measure is necessary to prevent severe
D. The drug is quickly inactivated by serum
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Q55607.ย Glyceryl trinitrate is generally taken by
A. Oral route
B. Intravenous route
C. Sublingual route
D. Subcutaneous route
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Q55608.ย Which of the following is longest acting nitrate?
A. Glyceryl trinitrate
B. Ethyt tetranitrate
C. Octyl nitrite
D. Pentaerythritol tetranitrate
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Q55609.ย Methaemoglobinaemia can occur with high doses of
A. Digitalis
B. Nitrites
C. Propranolol
D. All of the above
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Q55610.ย Cardiac glycoside consists of
A. Aminoacids and sugar
B. A steroid combined with sugar residue
C. A polypeptide and sugar
D. None of the above
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Q55611.ย Vascoconstriction is produced by following agent
A. Sympathomimetic amines
B. Eicosanoids
C. Endothelin
D. All of the above
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Q55612.ย Perhexillene meleate is a
A. Vasodilator drug
B. Cardiotonic drug
C. Antihyperlipidaemic drug
D. Urinary antiseptic
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Q55613.ย The dose of verapamil is
A. 4 to 6 gms per day
B. 40 to 80 gms thrice daily
C. 1 to 10 mg thrice daily
D. 250 mg once daily
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