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Questions from standard medical textbooks with detailed explanations

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PharmacologyDrugs Acting On Autonomous Nervous System
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Q55514. A 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of

A.Agranulocytosis
B.Gallstones
C.Lactic acidosis
D.Myopathy

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Q55515. Regarding verapamil, which one of the following statements is false?

A.Angina pectoris is an important indication
B.Contraindicated in the asthmatic patient
C.Relaxes vascular smooth muscle
D.Slows the depolarization phase of the action

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Q55516. What drug is used to prevent embolism in the lung and during myocardial infarction?

A.Alteplase
B.Human growth hormone
C.Granulocyte–macrophage colony – stimulating
D.EPOGEN (EPO)

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Q55517. Which of the following cardiovascular agents is classified chemically as a gly- coside?

A.Nifedipine
B.Digoxin
C.Flecainide
D.Cholestyramine

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Q55518. Inhibition of carbonic anhydrase results in

A.Abolition of NaHCO3 reabsorption in
B.Enhanced of NaHCO3 reabsorption in
C.Enhanced NAHCO3 secretion in distal tubule
D.None of the above

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Q55519. Which of the following cyclotron produced radiopharmaceuticals is used for assessing regional myocardial perfusion as part of an exercise stress test?

A.Thallous chloride 201TI USP
B.Sodium iodide 123I
C.Gallium citrate 67Ga USP
D.Indium 111In pentetate

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Q55520. Mary has a family history of heart disease and wonders if garlic would be beneficial to her. Which of the following statements is correct about garlic?

A.Enteric-coated tablets release their contents
B.Side effects include heartburn, flatulence, and
C.The safety of garlic in pregnancy is unknown
D.Garlic does not interact with warfarin

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Q55521. Exertion–induced angina, which is relieved by rest, nitroglycerin, or both, is referred to as

A.Prinzmetal’s angina
B.Unstable angina
C.Classic angina
D.Variant angina

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Q55522. Myocardial oxygen demand is increased by all of the following factors except

A.Exercise
B.Smoking
C.Cold temperatures
D.Isoproterenol

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Q55523. Which of the following agents used in prinzmetal’s angina has spasmolytic actions, which increase coronary blood supply?

A.Nitroglycerin
B.Nifedipine
C.Timolol
D.Isosorbide mononitrate

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Q55524. The oral absorption of following osmotic diuretic is negligible

A.Glycerin
B.Mannitol
C.Isosorbide
D.All of the above

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Q55525. Maximal medical therapy for treating angina pectoris is represented by which of the following choices?

A.Diltiazem, verapamil, nitroglycerin
B.Atenolol, isoproterenol, diltiazem
C.Verapamil, nifedipine, propranolol
D.Isosorbide, atenolol, diltiazem

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Q55526. The term ischemic heart disease (IHD) is used to designate all of the following conditions except

A.Angina pectoris
B.Sudden cardiac death
C.Congestive heart failur (CHF)
D.Arrhythmias

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Q55527. Which of the following thrombolytic agents would be appropriate at this time?

A.Anisoylated plasminogen streptokinase
B.Streptokinase (SK)
C.Recombinant tissue-type plasminogen

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Q55528. Strong anticholinergic effects limit the antiarrhythmic use of

A.Quinidine
B.Procainamide
C.Tocainide
D.Flecainide

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Q55529. Following loop diuretic is a phynoxy acetic acid derivative

A.Furosemide
B.Bumetanide
C.Ethacrynic acid
D.All of the above

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Q55530. Following potassium sparing diuretic is a mineralocorticoid receptor antagonist

A.Amiloride
B.Triamterene
C.Spironolactone
D.All of the above

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Q55531. A patient receiving a class I antiarrhyth- mic agent on a chronic basis complains of fatigue, low-grade fever, and joint pain suggestive of systemic lupus erythe- matosus (SLE). The patient is most likely receiving

A.Lidocaine
B.Procainamide
C.Quinidine
D.Flecainide

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Q55532. Which of the following drugs is a class IV antiarrhythmic that is primarily indicated for the treatment of supraventricular tachyarrhythmias?

A.Lbutilide
B.Mexiletine
C.Diltiazem
D.Quinidine

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Q55533. Which of the following agents has a direct effect on the AV mode, delaying calcium- channel depolarization?

A.Lidocaine
B.Diltiazem
C.Bretylium
D.Quinidine

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