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PharmacologyGeneral
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Q55234. In celiac disease oral absorption of which of the following drugs is decreased

A.Amoxycillin
B.Cephalexin
C.Cotrimoxazole
D.All the above

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MCQs in PharmacologyGeneral
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Q55235. Which people are said to be slowest acetylators because they metabolize isoniazid by the process of acetylation very slowly

A.Canadian Eskimos
B.Indians
C.Asiatic Jews
D.Chinese

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MCQs in PharmacologyGeneral
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Q55236. Which people are said to be fastest acetylators because they metabolize isoniazid by the process of acetylation very quickly

A.Canadian Eskimos
B.Indians
C.Asiatic Jews
D.Chinese

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MCQs in PharmacologyGeneral
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Q55237. Clearance of which of the following drugs is reduced parallel to decrease in the creatine clearance

A.Aminoglycosides (b) Digoxin
B.Phenobarbitone
C.All the above

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MCQs in PharmacologyGeneral
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Q55238. Pharmaceutical factors which can modify the effect of drug are

A.Formulation type
B.Bioavailabiligy
C.Bioequivalence
D.Fixed Dose combination

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Q55239. Following statement is true about receptors linked directly to ion channels

A.These receptors are involved mainly in fast
B.These are monomeric proteins containing
C.Ligand binding and channel opening occur
D.All of the above

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MCQs in Pharmacology
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Q55240. Route of administration suitable for emergency and permits titration of the dosage as well is

A.Oral
B.Intravenous
C.Intramuscular
D.Subcutaneous

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MCQs in PharmacologyGeneral
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Q55241. The disadvantage of oral route is

A.Vomiting as a result of gastrointestinal
B.Destruction of some drugs by the digestive
C.Irregularities in the absorption in the presence
D.Patient non-compliance

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MCQs in Pharmacology
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Q55242. Drugs which have a tendency to accumu- late in the body fat mostly have

A.Extremely high lipid-water partition co-
B.Extremely low lipid-water partition co-efficient
C.None of the above

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Q55243. Once the drug enters the blood, the rate at which it subsequently penetrates the tissues and other body fluids depends on

A.Capillary permeability
B.Extent of plasma protein and tissue binding
C.Transport mechanism
D.All the above

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MCQs in Pharmacology
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Q55244. Factor which can effect the absorption of drug is

A.Dissolution rate
B.Particle Size
C.Lipid Solubility
D.All the above

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Q55245. The movement of drug molecules across the cell membrane is by

A.Diffusion through the lipid
B.Diffusing through aqueous pores that traverse
C.Combination with a carrier molecule which
D.Pinocytosis

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MCQs in Pharmacology
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Q55246. Which of the following responses develops to drugs due to antigen-antibody reaction ?

A.Toxic response
B.Idiosyncratic response
C.Allergic response
D.None of the above

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Q55247. The microsomal oxidation of drugs is carried out through a larger or smaller extent in

A.Liver
B.Kidney
C.Lung
D.small intestine

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Q55248. The mechanism of Biotransformation of Aspirin to Salicylic acid and Acetic acid is

A.Oxidation
B.Reduction
C.Hydrolysis
D.None of the above

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Q55249. Which one of the statements regarding microsomal enzymes is not correct

A.They lack specificity
B.Capable of metabolizing substances of
C.Only catalyze reaction of compounds which
D.All the above

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Q55250. Which one of the following is a Phase II – Drug metabolizing reaction

A.Oxidation
B.Reduction
C.Acetylation
D.All the above

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Q55251. The metabolic reaction which makes the metabolite of codeine more Pharmaco- logically potent analgesic is

A.Dealkylation
B.Oxidation
C.Deamination
D.All the above

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Q55252. Prodrug

A.Facilitates absorption and distribution of
B.Increases the duration of action of drugs that
C.Promotes Site specific delivery of drugs
D.All the above

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Q55253. The removal of oxygen or an alteration in a drug which leads to a decrease in the proportion of oxygen in the drug compound is known as

A.Oxidation
B.Reduction
C.Hydrolysis
D.All the above

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MCQs in PharmacologyGeneral
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