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PharmacologyGeneral
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Q55194. Simultaneous administration of two drugs may – (select the false statement)

A.Show an additive effect
B.Produce synergism
C.Result in antagonism
D.Produce any of above phenomena

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MCQs in PharmacologyGeneral
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Q55195. The advantages of bio-assay over chemical assay include – (select false statement)

A.It is cheaper
B.The active principal does not have to be
C.The active principal does not have to be in a
D.The sensitivity may be greater

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MCQs in Pharmacology
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Q55196. In presence of competitive antagonist

A.The maximum response of agonist can never
B.The maximum can be achieved by increasing
C.Maximum can be achieved only if the
D.None of the above

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MCQs in PharmacologyGeneral
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Q55197. The receptor concept was first introduced by

A.J.N. Langley in 1878
B.Paul Ehrlich in 1926
C.Somonis in 1964
D.Wakesman in 1826

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Q55198. True tolerance develops because of

A.Diminition in absorption
B.Rapid excretion of the drug
C.Both of the above
D.None of the above

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Q55199. Two drugs binding to the same receptors is

A.Chemical antagonism
B.Pharmacokinetic antagonism
C.Competitive antagonism
D.Non-competitive antagonism

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Q55200. Tachyphylaxis is

A.A drug interaction between two similar types
B.Rapidly developing tolerance
C.A synergism between two types of drugs
D.None of the above

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Q55201. Drug A in a dose of 10 mg produces same response as with 100 mg of drug B

A.Drug A is 10 times more potent than drug B
B.Drug B is 10 times more potent than drug A
C.Drug A is 10 times more efficacious than
D.Both are equally potent

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MCQs in Pharmacology
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Q55202. Teratogenicity is

A.The acute reaction to drugs
B.Intolerance to drugs
C.Tumour forming action of the drugs
D.Malformation of the foetus

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Q55203. The chances of foetal malformation with a teratogenic drug is maximum

A.During first trimester of pregnancy
B.During second trimester of pregnancy
C.During third trimester of pregnancy
D.When given just prior to the labor

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Q55204. Phocomelia is a known teratogenic effect of

A.Anticancer drugs
B.Antiviral drugs
C.Antiepileptic drugs
D.Thalidomide

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Q55205. Which of the following drugs are known to cause toxic cataract?

A.Chloroquine
B.Ergot
C.Phenothiazine
D.Naphthalene

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Q55206. The passage of drugs into the foetus from placenta

A.Is by active transport
B.Is by passive diffusion
C.Is by carrier mediated transport
D.By any of the above methods

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Q55207. Idiosyncrasy reaction of a drug is

A.A type of hypersensitivity reaction
B.A type of drug antagonism
C.Unpredictable, inherent, qualitatively
D.Quantitatively exaggerated response

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Q55208. Two drugs having similar effects are termed as

A.Heterergic drugs
B.Isomer drugs
C.Homergic drugs
D.Antagonistic drugs

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Q55209. If the combined effect of two drugs acting by the same mechanism is equal to the allegebric sum of their individual effect, it is called as

A.Antagonism
B.Additive effect
C.Potentiation
D.None of the above

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Q55210. Antagonism between barbiturate and amphetamine is termed as

A.Non-competitive antagonism
B.Physiological antagonism
C.Competitive antagonism
D.Synergism

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Q55211. Which one of the following is an example of physical or chemical interaction?

A.Warfarin plus salicylates–prolongation of
B.Methotrexate plus sulfonamides–pancytopenia
C.Heparin plus protamine–reversal of heparin
D.Sulfonamides plus salicylate–sulfa toxicity

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Q55212. First order kinetics of the drugs is called when

A.A constant fraction of the drug is removed in
B.A constant amount of the drug is removed in
C.Total amount of the drug is removed in one
D.Total amount of the drug is removed in first

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Q55213. For the drugs which follow first order kinetics, after 4 half life the elimination will be approximately

A.40%
B.94%
C.25%
D.4%

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