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PaediatricsGeneral Pediatrics
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Q6937. On medical check up of a Punjabi student following findings were seen Hb of 9.9gm/d1, RBC count of 5.1 million, MCV of 62.5 fl and RDW of 13.51%. What is the most probable diagnosis ?

A.HbD
B.Thalassemia trait
C.Iron deficiency anemia
D.Anemia of chronic disease

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BiochemistryVitamins & Minerals
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Q6938. Megaloblastic anemia should be treated with both folic acid vitamin B12 because :

A.Folic acid alone causes improvement of hematologic symptoms
B.It is a Co factor
C.It is enzyme
D.None of the above

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BiochemistryVitamins & Minerals
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Q6939. Which of the following statements regarding the schilling test for vitamin B12 malabsorption is most accurate?

A.The schilling test results are abnormal in patients with dietary
B.In patients with pernicious anemia, the results of the schilling
C.In patients with ileal disease, the results of the schilling test
D.Pancreatic exocrine insufficiency does not cause schilling test

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MedicineHematology
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Q6940. Mentzer index more than 13 suggests a diagnosis of

A.Iron deficiency anemia
B.Thalassemia
C.Hereditary Spherocytosis
D.Autoimmune Hemolytic Anemia

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RadiologyGeneral Radiology
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Q6941. Which of the following statements about iron deficiency anemia is correct

A.Decreased TIBC
B.Increased ferritin levels
C.Bone marrow iron is decreased after serum iron is decreased
D.Bone marrow iron is decreased earlier than serum iron

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PsychiatryMood Disorders
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Q6942. Direct Coomb's test detects:

A.Antibodies attached to RBC Surface
B.Antibodies in the serum
C.Antigens attached to RBC Surface
D.Antigens in the serum

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ENTEar
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Q6943. All of following cause intravascular hemolysis, except

A.Mismatched blood transfusion
B.Paroxysmal cold hemoglobinuria
C.Thermal burns
D.Hereditary spherocytosis

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PsychiatryMood Disorders
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Q6944. Which of the following is not seen in Hereditary Spherocytosis

A.Direct Coomb's Positive
B.Increased Osmotic Fragility
C.Splenomegaly
D.Gall stones

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MicrobiologyVirology
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Q6945. Usually associated with parvovirus B19 infection in those with hereditary spherocytosis

A.Mild to moderate splenomegaly
B.Aplastic crisis
C.Gallstones
D.Hemolytic crisis

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RadiologyNuclear Medicine
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Q6946. With regards to hereditary spherocytosis, which of the following is false

A.Usually has autosomal dominant inheritance
B.Caused by mutations in genes for proteins such as spectrin,
C.Red blood cells are destroyed in the spleen
D.Aplastic crises are common

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Q6947. All of the following are true regarding splenectomy in patients with hereditary spherocytosis, except ?

A.Avoid in mild cases
B.Delay splenectomy until at least 4 years old age
C.Anti-pneumococcal vaccination must be given before
D.Prolonged anti-pneumococcal antibiotic prophylaxis must be

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AnatomyHead & Neck
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Q6948. Most common heavy chain disease is

A.Franklin disease
B.Seligmann disease
C.Mu heavy chain disease
D.Waldenstrom cryoglobulinemia

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Q6949. Leukoerythroblastic picture may be seen in all of the following conditions, except:

A.Myelofibrosis
B.Metastatic carcinoma
C.Gaucher's disease
D.Thalassemia

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PaediatricsGeneral Pediatrics
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Q6950. Chronic Non-Spherocytic hemolytic anemia is seen in which class of G6PD deficiency

A.Class I
B.Class II
C.Class III
D.Class IV

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MicrobiologyParasitology
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Q6951. Sickle cell anemia leads to resistance towards?

A.P. falciparum
B.P. ovale
C.P. malariae
D.P. vivax

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PaediatricsGeneral Pediatrics
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Q6952. Which of the following is a quantitative defect in globin synthesis

A.Thalassemia
B.Sickle cell hemoglobinopathy
C.G6PD deficiency
D.Diamond-Black fan syndrome

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BiochemistryEnzymes & Proteins
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Q6953. The most important diagnositic feature for beta thalassemia trait

A.Raised HbF
B.Reduced MCH
C.Reduced MCV
D.Raised HbA2

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PsychiatryMood Disorders
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Q6954. Deletion of one alpha globin gene on one chromosome is best defined as

A.Hb Barts hydrops fetails
B.Alpha thalassemia major
C.Alpha thalassemia trait
D.Alpha thalassemia silent carrier

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PsychiatryMood Disorders
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Q6955. Which of the following is caused by deletion of all four alpha globin genes

A.Beta thalassemia major
B.Hb Barts
C.HbH
D.a° thalassemia trait

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BiochemistryNucleotide Metabolism
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Q6956. In Beta thalassemia, the most common gene mutation is

A.Intron 1 inversion
B.Intron 22
C.619 bp deletion
D.3.7 bp deletion

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