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BiochemistryNucleic Acids
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Q51800. Daily uric acid excretion in adult men is

A.2–6 mg
B.20–40 mg
C.150–250 mg
D.40–600 mg

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51801. Dietary purines are catabolised in

A.Liver
B.Kidneys
C.Intesitnal mucosa (D) All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51802. De novo synthesis of pyrimidine nucle- otides occurs in

A.Mitochondria
B.Cytosol
C.Microsomes
D.Ribosomes

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51803. An enzyme common to de novo synthesis of pyrimidine nucleotides and urea is

A.Urease
B.Carbamoyl phosphate synthetase
C.Aspartate transcarbamoylase
D.Argininosuccinase

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51804. The nitrogen atoms of pyrimidine nucleus are provided by

A.Glutamate
B.Glutamate and aspartate
C.Glutamine
D.Glutamine and aspartate

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51805. The carbon atoms of pyrimidine nucleus are provided by

A.Glycine and aspartate
B.CO2 and aspartate
C.CO2 and glutamate
D.CO2 and glutamine

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51806. Nitrogen at position 1 of pyrimidine nu- cleus comes from

A.Glutamine
B.Glutamate
C.Glycine
D.Aspartate

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51807. Nitrogen at position 3 of pyrimidine nu- cleus comes from

A.Glutamine
B.Glutamate
C.Glycine
D.Aspartate

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51808. The carbon atom at position 2 of pyrimi- dine nucleus is contributed by

A.CO2
B.Glycine
C.Aspartate
D.Glutamine

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51809. Aspartate contributes the following carbon atoms of the pyrimidine nucelus:

A.C2 and C4
B.C5 and C6
C.C2, C4 and C6
D.C4, C5 and C6

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51810. The first pyrimidine nucleotide to be formed in de novo synthesis pathway is

A.UMP
B.CMP
C.CTP
D.TMP

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51811. Conversion of uridine diphosphate into deoxyuridine diphosphate requires all the following except

A.Ribonucleotide reductase
B.Thioredoxin
C.Tetrahydrobiopterin
D.NADPH

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51812. Amethopterin and aminopterin decrease the synthesis of

A.TMP
B.UMP
C.CMP
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51813. For synthesis of CTP and UTP, the amino group comes from

A.Amide group of Asparagine
B.Amide group of glutamine
C.α-Amino group of glutamine
D.α-Amino group of glutamate

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51814. CTP synthetase forms CTP from

A.CDP and inorganic phosphate
B.CDP and ATP
C.UTP and glutamine
D.UTP and glutamate

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51815. For the synthesis of TMP from dump, a coenzyme is required which is

A.N10- Formyl tetrahydrofolate
B.N5- Methyl tetrahydrofolate
C.N5, N10- Methylene tetrahydrofolate
D.N5- Formimino tetrahydrofolate

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51816. All the enzymes required for de novo synthesis of pyrimidine nucleotides are cytosolic except

A.Carbamoyl phosphate synthetase
B.Aspartate transcarbamoylase
C.Dihydro-orotase
D.Dihydro-orotate dehydrogenase

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51817. During de novo synthesis of pyrimidine nucleotides, the first ring compound to be formed is

A.Carbamoyl aspartic acid
B.Dihydro-orotic acid
C.Orotic acid
D.Orotidine monophosphate

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51818. Tetrahydrofolate is required as a coen- zyme for the synthesis of

A.UMP
B.CMP
C.TMP
D.All of these

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51819. All of the following statements about thioredoxin reductase are true except:

A.It requires NADH as a coenzyme
B.Its substrates are ADP, GDP, CDP and UDP
C.It is activated by ATP
D.It is inhibited by dADP

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MCQs in Biochemistry
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Nucleic Acids
Nucleic Acids
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