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BiochemistryNucleic Acids
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Q51640. The distance spanned by one turn of B- form DNA is

A.1.0 nm
B.2.0 nm
C.3.0 nm
D.3.4 nm

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51641. In a DNA molecule the thymine concen- tration is 30%, the guanosine concentra- tion will be

A.10%
B.20%
C.30%
D.40%

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51642. IN a DNA molecule, the guanosine content is 40%, the adenine content will be

A.10%
B.20%
C.30%
D.40%

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51643. An increased melting temperature of du- plex DNA results from a high content of

A.Adenine + Guanine
B.Thymine + Cytosine
C.Cytosine + Guanine
D.Cytosine + Adenine

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51644. A synthetic nucleotide analogue, 4-hydro- xypyrazolopyrimidine is used in the treatment of

A.Acute nephritis
B.Gout
C.Cystic fibrosis of lung
D.Multiple myeloma

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51645. A synthetic nucleotide analogue, used in the chemotherapy of cancer and viral infections is

A.Arabinosyl cytosine
B.4-Hydroxypyrazolopyrimidine
C.6-Mercaptopurine
D.6-Thioguanine

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51646. Histamine is formed from histidine by the enzyme histidine decarboxylase in the presence of

A.NAD
B.FMN
C.HS-CoA
D.B6-PO4

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51647. Infantile convulsions due to lesser formation of gamma amino butyric acid from glutamic acid is seen in the de- ficiency of

A.Glutamate-dehydrogenase
B.Pyridoxine
C.Folic acid
D.Thiamin

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51648. Which of the following amino acids pro- duce a vasoconstrictor on decarboxyla- tion?

A.Histidine
B.Tyrosine
C.Threonine
D.Arginine

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51649. The degradation of RNA by pancreatic ribonuclease produces

A.Nucleoside 2-Phosphates
B.Nucleoside 5′-phosphates
C.Oligonucleosides
D.Nucleoside 3′-phosphate and oligonucleotide

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51650. Intestinal nucleosidases act on nucleo- sides and produce

A.Purine base only
B.Phosphate only
C.Sugar only
D.Purine or pyrimidine

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51651. In purine biosynthesis carbon atoms at 4 and 5 position and N at 7 position are contributed by

A.Glycine
B.Glutamine
C.Alanine
D.Threonine

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51652. N10-formyl and N5N10-methenyl tetrahy- drofolate contributes purine carbon atoms at position

A.4 and 6
B.4 and 5
C.5 and 6
D.2 and 8

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51653. In purine nucleus nitrogen atom at 1 position is derived from

A.Aspartate
B.Glutamate
C.Glycine
D.Alanine

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51654. The key substance in the synthesis of purine, phosphoribosyl pyrophosphate is formed by

A.α-D-ribose 5-phosphate
B.5-phospho β-D-ribosylamine
C.D-ribose
D.Deoxyribose

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51655. In purine biosynthesis ring closure in the molecule formyl glycinamide ribosyl-5- phosphate requires the cofactors:

A.ADP
B.NAD
C.FAD
D.ATP and Mg++

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51656. Ring closure of formimidoimidazole carboxamide ribosyl-5-phosphate yields the first purine nucleotide:

A.AMP
B.IMP
C.XMP
D.GMP

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51657. The cofactors required for synthesis of adenylosuccinate are

A.ATP, Mg++
B.ADP
C.GTP, Mg++
D.GDP

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q51658. Conversion of inosine monophosphate to xanthine monophosphate is catalysed by

A.IMP dehydrogenase
B.Formyl transferase
C.Xanthine-guanine phosphoribosyl transferase
D.Adenine phosphoribosyl transferase

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51659. Phosphorylation of adenosine to AMP is catalysed by

A.Adenosine kinase
B.Deoxycytidine kinase
C.Adenylosuccinase
D.Adenylosuccinate synthetase

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MCQs in BiochemistryNucleic Acids
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Nucleic Acids