MCQ Book Questions

Q60082. Which of the following proteins helps stimulate healing and angiogenesis in the wound of the patient described in Ques- tion 6?

Q60083. A 68-year-old man presents for repair of an abdominal aortic aneurysm. Severe complicated atherosclerosis is noted at sur- gery, prompting concern for embolism of atheromatous mate- rial to the kidneys and other organs. If the patient were to develop a renal cortical infarct as a result of surgery, which of the following would be the most likely outcome?

Q60084. A 40-year-old woman presents with a painless lesion on her right ear lobe (shown in the image). She reports that her ears were pierced 4 months ago. Which of the following best explains the pathogenesis of this lesion?

Q60085. A 16-year-old boy suffers a concussion during an ice hockey game and is rushed to the emergency room. A CT scan of the brain reveals a cerebral contusion of the left frontal lobe. The boy lies comatose for 3 days but eventually regains consciousness. Which of the following cells is the principal mediator of scar formation in the central nervous system of this patient?

Q60086. A 30-year-old fi refi ghter suffers extensive third-degree burns over his arms and hands. This patient is at high risk for developing which of the following complications of wound healing?

Q60087. A 23-year-old man suffers a crush injury of his foot, which becomes secondarily infected. He undergoes a below-the-knee amputation. Six months later, the patient complains of chronic pain at the site of amputation. A fi rm nodule is identifi ed at the scar site. A biopsy of the nodule demonstrates haphazard growth of nerves (shown in the image). Which of the follow- ing is the most likely diagnosis?

Q60088. A 34-year-old woman has a benign nevus removed from her back under local anesthesia. Which of the following families of cell adhesion molecules is the principal component of the “provisional matrix” that forms during early wound healing?

Q60089. Which of the following families of glycoproteins plays the most important role in regulating the migration and differen- tiation of leukocytes and connective tissue cells during wound healing in the patient described in Question 14?

Q60090. A 29-year-old carpenter receives a traumatic laceration to her left arm. Which of the following is the most important fac- tor that determines whether this wound will heal by primary or secondary intention?

Q60091. Activated fi broblasts, myofi broblasts, and capillary sprouts are most abundant in the wound of the patient described in Ques- tion 16 at which of the following times after injury?

Q60092. A 9-year-old boy receives a deep laceration over his right eye- brow playing ice hockey. The wound is cleaned and sutured. Which of the following describes the principal function of macrophages that are present in the wound 24 to 48 hours after injury?

Q60093. Which of the following collagens is deposited fi rst during wound healing in the patient described in Question 18?

Q60094. A 35-year-old man asks for advice regarding seasonal eye itching and runny nose. Recurrent conjunctivitis in this patient is most likely caused by which of the following mechanisms of disease?

Q60095. An 8-year-old boy presents with periorbital edema and throbbing headaches. His parents report that the boy had a “strep throat” 2 weeks ago. Urinalysis shows 3+ hematuria. A renal biopsy shows hypercellular glomeruli, and electron microscopic examination of glomeruli discloses subepithelial “humps.” Which of the following best explains the pathogenesis of glomerulonephritis in this patient?

Q60096. A 21-year-old woman presents with a 3-month history of malaise, joint pain, weight loss, and sporadic fever. The patient appears agitated. Her temperature is 38°C (101°F). Other physical fi ndings include malar rash, erythematous- pink plaques with telangiectatic vessels, oral ulcers, and nonblanching purpuric papules on her legs. Laboratory studies show elevated levels of blood urea nitrogen and creatinine. Antibodies directed to which of the following antigens would be expected in the serum of this patient?

Q60097. Serum levels of complement proteins may be reduced during the active phase of disease in the patient described in Question 3 due to which of the following mechanisms of disease?

Q60098. A 45-year-old woman complains of severe headaches and diffi culty swallowing. Over the past 6 months, she has noticed small, red lesions around her mouth as well as thickening of her skin. The patient has “stone facies” on physical examination. Which of the following antigens is the most common and most specifi c target of autoantibody in patients with this disease?

Q60099. A skin biopsy in the patient described in Question 5 would most likely show a perivascular accumulation of which of the following extracellular matrix proteins?

Q60100. During the physical examination of a 22-year-old man, a puri- fi ed protein derivative isolated from Mycobacterium tubercu- losis is injected into the skin. Three days later, the injection site appears raised and indurated. Which of the following glycoproteins was directly involved in antigen presentation during the initiation phase of delayed hypersensitivity in this patient?

Q60101. A 52-year-old woman with a history of systemic hypertension and chronic renal failure undergoes kidney transplantation, but the graft fails to produce urine. A renal biopsy is diag- nosed as “hyperacute transplant rejection.” Graft rejection in this patient is caused primarily by which of the following mediators of immunity and infl ammation?