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PharmacologyDrugs Used In Endocrine Disorders
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Q55794.ย Glucocorticoids have not been proved to be effective in the treatment of

A.Acute lymphocytic leukemia
B.Addisonโ€™s disease
C.Asthma
D.Chemotherapy-inhduced vomiting

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Q55795.ย For patients who have been on long-term therapy with a glucocorticoid and who now wish to discontinue the drug, gradual tapering of the glucocorticoid is needed to allow recovery of

A.Depressed release of insulin from pancreatic
B.Hematopoiesis in the bone marrow
C.Normal osteoblast function
D.The control by vasopressin of water excretion

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Q55796.ย A 24-year-old woman with type 1 diabetes wishes to try tight control of her diabetes to improve her long-term prognosis. Which of the following regimens is most appropriate?

A.Morning injections of mixed lente and
B.Evening injections of mixed regular and lente
C.Morning and evening injections of regular
D.Morning injections of ultralente insulin,

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Q55797.ย Which of the following substances when present in urine is the most likely positive sign of pregnancy?

A.Thyroid-stimulating hormone (TSH)
B.Corticotropin
C.Human chronic gonadotropin (HCG)
D.Interstitial cell-stimulating hormone (ICSH)

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Q55798.ย A 54-year-old obese patient with type 2 diabetes and a history of alcoholism probably should not receive metformin because it can increase his risk of

A.A disulfiram-like reaction
B.Excessive weight gain
C.Hypoglycemia
D.Lactic acidosis

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Q55799.ย Which of the following drugs is taken during the first part of a meal for the purpose of delaying the absorption of dietary carbohydrates?

A.Acarbose
B.Colestipol
C.Glipizide
D.Pioglitazone

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Q55800.ย Which of the following drugs is most likely to cause hypoglycemia when used as monotherapy in the treatment of type 2 diabetes?

A.Acarbose
B.Glyburide
C.Metformin
D.Miglitol

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Q55801.ย In the treatment of hypothyroidism, thyroxine is preferred over liothyronine because thyroxine

A.Can be made more easily by recombinant
B.Has a longer half-life
C.Has higher affinity for thyroid hormone
D.Is faster acting

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Q55802.ย A young woman seeks advice because she had unprotected sexual intercourse 12 hours earlier. Based on her menstrual cycle, she believes that conception is possible. Which of the following drugs should she use as a postcoital contraceptive?

A.Clompihene
B.Diethylstilbestrol plus raloxifene
C.Ethinyl estradiol combined with norethindrone
D.Flutamide

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Q55803.ย All of the following hormonal drugs possess a steroidal nucleus except

A.Ethinyl estradiol
B.Nonethindrone
C.Liothyronine
D.Prednisolone

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Q55804.ย Which one of the following statements about hormone replacement therapy (HRT) regimens in menopause is accurate?

A.It commonly includes a progestin to reduce
B.It has been shown in clinical trials to reduce
C.It includes steroids that induce cytochrome
D.It should be avoided in women with a history

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Q55805.ย Hypercoagulability and dermal vascular necrosis due to protein C deficiency is known to be an earlyโ€“appearing adverse effect of treatment with

A.Aspirin
B.Clopidogrel
C.Heparin
D.Streptokinase

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Q55806.ย A 42-year-old woman requires treatment for diabetes insipidus following surgical removal of part of her pituitary gland. The advantage of treating this patient with desmopressin instead of vasopressin is that desmopressin

A.Causes less formation of factor VIII
B.Causes less hypernatremia
C.Causes less hyperprolactinemia
D.Is more selective for the V2 receptor subtype

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Q55807.ย All of the following substances are endogenous tropic hormones secreted by the pituitary gland except

A.Somatotropin
B.Human Chorionic Gonadotropin (HCG)
C.Follicle-timulating hormone (FSH)
D.Thyroid-stimulating hormone (TSH)

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Q55808.ย Which of the following substances when present in urine is the most likely positive sign of pregnancy?

A.Thyroidโ€“stimulating hormone (TSH)
B.Corticotropin (ACTH)
C.Human chorionic gonadotropin (HCG)
D.Interstital cell-stimulating hormone (ICSH)

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Q55809.ย Which of the following glucocorticoids produces the least sodium retention?

A.Corticosone
B.Hydrocorticosone
C.Prednisolone
D.Dextramethasone

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Q55810.ย Which of the following glucocorticoids produces the least sodium retention?

A.Cortisone
B.Hydrocortisone
C.Prednisolone
D.Dexamethasone

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Q55811.ย Which of the following insulins can be administered intravenously?

A.Regular insulin
B.Isophane insulin (NPH)
C.Protamine zinc insulin (PZi)
D.Semilente insulin

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Q55812.ย Which of the following classes of compounds stimulates the release of insulin from pancreatic ฮฒ-cells?

A.Progestins
B.Biguanides
C.ฮฑ-Glucosidase inhibitors
D.Thiourylenes

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Q55813.ย Insulin preparations that contain a modifying protein include

A.Lente insulin
B.Regular insulin
C.Isophane insulin (NPH)

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