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PharmacologyDrugs Acting On Autonomous Nervous System
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Q55734. A 23-year-old male with a history of influenza A infection. An outbreak of influenza A has just been reported in his community and he is exhibiting initial symptoms of influenza A. Which agent would be the most useful to treat him?

A.Cidofovir
B.Famciclovir
C.Rimantidine
D.Foscarnet

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Q55735. Addition of clavulanic acid to amoxicillin is to

A.Decrease the renal excretion of amoxicillin
B.Enhance the anti-bacterial activity of
C.Decrease the biotransformation of amoxicillin
D.To increase oral absorption of amoxicillin

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Q55736. The aminoglycoside that can be used in amoebiasis is

A.Paromomycin
B.Framycetin
C.Amikacin
D.Netilmicin

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Q55737. Tetracyclines are avoided in pregnancy because they can

A.Cause abortions
B.Cause excessive postpartum hemorrhage
C.Affect the bones and teeth of the fetus
D.Cause excessive vomiting in the mother

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Q55738. Ciprofloxacin inhibits the bacterial enzyme

A.Transpeptidase
B.DNA gyrase
C.DNA dependent RNA polymerase
D.Dihydrofolate reductase

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Q55739. Erythromycin is the drug of choice in

A.Pertussis
B.Gonococcal urethritis
C.Prophylaxis of bacterial endocarditis
D.Chlamydial infections

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Q55740. Cyclosporine

A.Is derived from a bacterium
B.Has a selective inhibitory effect on T-
C.Is not absorbed orally
D.Is excreted unchanged from the body

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Q55741. Tetracycline is stored in the body in

A.Protein bound form
B.In hairs, nails and skin
C.In muscular tissues
D.In bones

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Q55742. Drug which interfere with the bacterial cell wall synthesis is

A.Chloramphenicol
B.Tetracyclines
C.Colistin
D.Penicillins and cephalosporins

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Q55743. Antibiotic(s) which inhibit the protein synthesis in cells is/are

A.Sulphonamides and PAS
B.Isonized and PAS
C.Tetracyclines and chloramphenicol
D.Penicillin and cephalosporins

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Q55744. Penicillins are not effective against

A.Gram-positive cocci
B.Gram-positive bacilli
C.Gram-negative bacilli
D.Gram-negative cocci

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Q55745. Pseudomonas aeruginosa organism is always sensitive to

A.Streptomycin
B.Colistin
C.Penicillin
D.Tetracyclines

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Q55746. Drug of choice for Brucella infection is

A.Tetracycline
B.Gentamycin
C.Ampicillin
D.Sulfonamides

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Q55747. Streptomycin is more active at

A.pH 5.5 than pH 8.5 of urine
B.pH 8.5 than pH 5.5 of urine
C.Equally active at all pH of urine
D.All of the above

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Q55748. Dr. Jones requests your help in prescrib- ing a protease inhibitor for his patient. He has heard that not all agents are the same and asks for your recommendation as to which agent would penetrate the blood-brain barrier. Which agent would you recomment?

A.Saquinavir
B.Ritonavir
C.Indinavir
D.Nelfinavir

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Q55749. Which of the following agents is not a broad spectrum antibiotic

A.Ampicillin
B.Tetracycline
C.Chloremphenicol
D.Gentamycin

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Q55750. Probenacid increases the plasma con- centration of penicillin because

A.It blocks the renal tubular excretion of
B.It prevents the metabolism of penicillin
C.It displaces penicillin from protein binding
D.It acts by all above mechanisms

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Q55751. Benzylpenicillin is not used orally because

A.It is destroyed by acid in stomach and
B.It is well absorbed from intestine but is
C.It produces severe diarrhoea on oral
D.All of the above

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Q55752. Penicillins should not be given by

A.Intramuscular route
B.Intravenous route
C.Intrathecal route
D.Intra – articular route

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Q55753. Anaphylactic shock to penicillin occurs

A.Almost at once after administration
B.Between 6 to 12 hrs of administration
C.Between 4 to 6 hrs of administration
D.After 12 hrs of administration

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