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PharmacologyGeneral
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Q55134.Β Monitoring plasma drug concentration is useful while using

A.Antihypertensive drugs
B.Levodopa
C.Lithium carbonate
D.MAO inhibitors

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MCQs in PharmacologyGeneral
PharmacologyGeneral
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Q55135.Β Microsomal enzyme induction has one of the following features

A.Takes about one week to develop
B.Results in increased affinity of the enzyme
C.It is irreversible
D.Can be used to treat acute drug poisonings

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MCQs in Pharmacology
PharmacologyGeneral
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Q55136.Β Which of the following is a competitive type of enzyme inhibitor

A.Acetazolamide
B.Disulfiram
C.Physostigmine
D.Theophyline

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MCQs in PharmacologyGeneral
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Q55137.Β What is true in relation to drug receptors

A.All drugs act through specific receptors
B.All drug receptors are located on the surface
C.Agonists induce a conformational change in
D.Partial agonists have low affinity for the

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MCQs in Pharmacology
PharmacologyGeneral
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Q55138.Β A partial agonist can antagonize the effects of a full agonist because it has

A.High affinity but low intrinsic activity
B.Low affinity but high intrinsic activity
C.No affinity and low intrinsic activity
D.High affinity but no intrinsic activity

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MCQs in Pharmacology
PharmacologyGeneral
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Q55139.Β Receptor agonists possess

A.Result in increased smooth endoplasmic
B.Result in increased rough endoplasmic reticulum
C.Result in decreased enzymes in the soluble
D.Require 3–4 months to reach completion

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MCQs in Pharmacology
PharmacologyGeneral
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Q55140.Β Agonists affect the receptor molecule in the following manner

A.Alter its amino acid sequence
B.Denature the receptor protein
C.Alter its folding or alignment of subunits
D.Induce covalent bond formation

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MCQs in Pharmacology
PharmacologyGeneral
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Q55141.Β Receptors perform the following function/ functions

A.Ligand recognition
B.Signal transduction
C.Both ligand recognition and signal
D.Disposal of agonists and antagonists

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MCQs in PharmacologyGeneral
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Q55142.Β Which of the following receptor types has 7 helical membrane, spanning amino acid segments with 3 extracellular and 3 intracellular loops

A.Tyrosine protein kinase receptor
B.Gene expression regulating receptor
C.Intrinsic ion channel containing receptor
D.G protein coupled receptor

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MCQs in Pharmacology
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Q55143.Β Which of the following is a G protein coupled receptor

A.Muscarinic cholinergic receptor
B.Nicotinic cholinergic receptor
C.Glucocorticoid receptor
D.Insulin receptor

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MCQs in PharmacologyGeneral
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Q55144.Β Placebo effects result presumably from the

A.Physician-patient relationship
B.Mental set up imparted by the therapeutic
C.Mental set up imparted by the physician
D.All of the above

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MCQs in PharmacologyGeneral
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Q55145.Β All of the following subserve as intracellular second messengers in receptor mediated signal transduction except

A.Cyclic AMP
B.Inositol trisphosphate
C.Diacyl glycerols
D.G protein

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MCQs in PharmacologyGeneral
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Q55146.Β A receptor which itself has enzymatic property is

A.Insulin receptor
B.Progesterone receptor
C.Thyroxine receptor
D.Glucagon receptor

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Q55147.Β Down regulation of receptors can occur as a consequence of

A.Continuous use of agonists
B.Continuous use of antagonists
C.Chronic use of CNS depressants
D.Denervation

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Q55148.Β When therapeutic effects decline both below and above a narrow range of doses, a drug is said to exhibit

A.Ceiling effect
B.Desensitization
C.Therapeutic window phenomenon
D.Nonreceptor mediated action

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MCQs in Pharmacology
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Q55149.Β β€˜Drug efficacy’ refers to

A.The range of diseases in which the drug is
B.The maximal intensity of response that can
C.The therapeutic dose range of the drug
D.The therapeutic index of the drug

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MCQs in PharmacologyGeneral
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Q55150.Β If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is

A.Highly potent
B.Highly efficacious
C.Highly toxic
D.Highly selective

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MCQs in PharmacologyGeneral
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Q55151.Β The therapeutic index of a drug is a measure of its

A.Safety
B.Potency
C.Efficacy
D.Dose variability

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MCQs in PharmacologyGeneral
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Q55152.Β If the effect of combination of two drugs is equal to the sum of their individual effects, the two drugs are exhibiting

A.Potentiation
B.Synergism
C.Cross tolerance
D.Antagonism

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Q55153.Β The antagonism between adrenaline and histamine is called β€˜Physiological anta- gonism’ because

A.Both are physiologically present in the body
B.They act on physiological receptors
C.Both affect many physiological processes
D.They have opposite physiological effects

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MCQs in Pharmacology
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