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PharmacologyGeneral
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Q55074. Which of the following terms best describes a co-factor that is firmly bound to an apoenzyme?

A.Holoenzyme
B.Prosthetic group
C.Coenzyme
D.Transferase

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Q55075. Enzymes that uncouple peptide linkages are best classified as

A.Hydrolases
B.Ligases
C.Oxidoreductases (d) Transferases

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Q55076. The sugar that is inherent in the nucleic acids RNA and DNA is

A.Glucose
B.Sucrose
C.Ribose
D.Digitoxose

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Q55077. N-oxidation will be involved with the metabolism of following drugs, except

A.Dapsone
B.Meperidine
C.Phenytoin
D.Chlorpheniramine

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Q55078. Which of the following statements describes plasmids? They

A.Are single – stranded DNA molecules
B.Carry optional gene(s)
C.Carry genes essential for growth
D.Are always found in linear form

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Q55079. Bacteria that grow at temperatures as high as 550C are known as

A.Psychrophiles
B.Thermophiles
C.Mesophiles
D.Auxotrophs

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Q55080. Which of the following organisms can use only molecular oxygen as the final acceptor?

A.Obligate anaerobes
B.Facultative anaerobes
C.Obligate aerobes
D.Strict anaerobes

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Q55081. A declining growth rate occurs during which of the following phases of bacterial cell growth?

A.Lag phase
B.Exponential phase
C.Stationary phase (d) Death phase

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Q55082. Which class of antibody has the longest serum half-life and opsonizes antigens for phagocytosis through two different pathways?

A.Immunoglobulin G (IgG)
B.Immunoglobulin M(IgM)
C.Immunoglobulin A (IgA)
D.Immunoglobulin E (IgE)

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Q55083. Urticaria that appears rapidly after the ingestion of food usually indicates which type of hypersensitivity reaction?

A.Type I
B.Type II
C.Type III
D.Type IV

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Q55084. A patient receives long-term, high-dose therapy with a sulfonamide. After approximately 3 weeks of therapy, the patient has a low-grade fever, rash, and muscle and joint pain. Which type of hypersensitivity accounts for these symptoms?

A.Type I
B.Type II
C.Type III
D.Type IV

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Q55085. CD4+T cells specifically recognize antigens in which form?

A.Bound to major histocompatibility (MHC)
B.In free, soluble form in extracellular fluids
C.Bound to MHC class II molecules on the

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Q55086. Which of the following statements concerning a drug receptor is true?

A.It mediates the nonspecific action of volatile
B.Its expression is induced only by exogenously
C.It can bind endogenous ligand to produce
D.It mediates the cathartic activity of

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Q55087. Which of the following acids has the highest degree of ionization in an aqueous solution?

A.Aspirin pKa = 3.5
B.Indomethacin pKa = 4.5
C.Warfarin pKa = 5.1
D.Ibuprofen pKa = 5.2

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Q55088. Which of the following salts forms an aqueous solution that is alkaline to litmus?

A.Sodium chloride
B.Benzalkonium chloride
C.Meperidine hydrochloride
D.Cefazolin sodium

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Q55089. Hydrolysis reaction are involved with the metabolism of following drugs, except

A.Procaine
B.Diazepam
C.Aspirin
D.Lidocaine

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Q55090. Flurazepam has pKa of 8.2. What percentage of flurazepam will be ionized at a urine pH of 5.2?

A.0.1%
B.1%
C.50%
D.99%

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Q55091. Precipitation may occur when mixing aqueous solutions of meperidine hydro- chloride with which of the following solutions?

A.Sodium bicarbonate injection
B.Atropine sulfate injection
C.Sodium chloride injection

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Q55092. The excretion of a weakly acidic drug generally is more rapid in alkaline urine than in acidic urine. This process occurs because

A.A weak acid in alkaline media will exist
B.A weak acid in alkaline media will exist in
C.All drugs are excreted more rapidly in an

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Q55093. Which of the following drugs is considered to be the agent of choice for anaphylactic reactions?

A.Edrophonium
B.Ipratropium
C.Ambenonium
D.Propantheline

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