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BiochemistryNucleic Acids
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Q52200.Β In the biosynthesis of c-DNA, the joining enzyme ligase requires

A.GTP
B.ATP
C.CTP
D.UTP

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q52201.Β Which one of the following binds to specific nucleotide sequences that are upstream and most distant from the start site?

A.RNA polymerase
B.Repressor
C.Inducer
D.Restriction

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q52202.Β Using written convention which one of the following sequences is complimentary to TGGCAGCCT?

A.ACCGTCGGA
B.ACCGUCGGA
C.AGGCTGCCA
D.TGGCTCGGA

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q52203.Β Ribosomes similar to those of bacteria found in

A.Plant nuclei
B.Cardiac muscle cytoplasm
C.Liver endoplasmic reticulum
D.Neuronal cytoplasm

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MCQs in BiochemistryNucleic Acids
BiochemistryNucleic Acids
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Q52204.Β The mechanism of synthesis of DNA and RNA are similar to all the following ways except

A.They involve release of pyrophosphate from
B.They require activated nucleotide precursor
C.The direction of synthesis is
D.They require a primer

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q52205.Β Template-directed DNA synthesis occurs in all the following except

A.The replication fork
B.Polymerase chain reaction
C.Growth of RNA tumor viruses
D.Expression of oncogenes

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MCQs in BiochemistryNucleic Acids
PharmacologyGeneral
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Q55000.Β All of the following are general mechanisms of drug permeation Except

A.Aqueous diffusion
B.Aqueous hydrolysis
C.Lipid diffusion
D.Pinocytosis or endocytosis

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MCQs in PharmacologyGeneral
PharmacologyGeneral
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Q55001.Β If the plasma concentration of a drug declines with β€œfirst-order kinetics”, this means that

A.There is only one metabolic path for drug
B.The half-life is the same regardless of the
C.The drug is largely metabolized in the liver
D.The rate of climination is proportionate to

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MCQs in Pharmacology
PharmacologyGeneral
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Q55002.Β Regarding termination of drug action

A.Drug must be exerted from the body to
B.Metabolism of drugs always increases their
C.Metabolism of drugs always abolishes their
D.Hepatic metabolism and renal excretion are

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MCQs in Pharmacology
PharmacologyGeneral
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Q55003.Β Distribution of drugs to specific tissues

A.Is independent of blood flow to the organ
B.Is independent of the solubility of the drug in
C.Depends on the unbound drug concentration
D.Is increased for drugs that are strongly bound

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MCQs in Pharmacology
PharmacologyGeneral
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Q55004.Β A physical process by which a weak acid becomes less water-soluble and more lipid-soluble at low pH is

A.Distribution
B.Elimination
C.First-pass effect
D.Permeation

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MCQs in PharmacologyGeneral
PharmacologyGeneral
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Q55005.Β Dose-response curves are used for drug evaluation in the animal laboratory and in the clinic, Quantal dose-response curves are often

A.Used for determining the therapeutic index
B.Used for determining the maximal efficacy
C.Invalid in the presence of inhibitors of the
D.Obtained from the study of intact subject but

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MCQs in Pharmacology
PharmacologyGeneral
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Q55006.Β The following are excreted faster in basic urine

A.Weak acids
B.Strong acids
C.Weak Bases
D.None of the above

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MCQs in PharmacologyGeneral
PharmacologyGeneral
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Q55007.Β Which of the following statements about spare receptors is most correct ?

A.Spare receptors, in the absence of drug, are
B.Spare receptors will be detected if the
C.Spare receptors influence the maximal
D.Spare receptors activate the effector

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MCQs in Pharmacology
PharmacologyGeneral
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Q55008.Β Which of the following terms best describes an antagonist that interacts directly with the agonist and not at all or only incidentally, with the receptor ?

A.Pharmacological antagonist
B.Partial agonist
C.Physiological antagonist
D.Chemical antagonist

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MCQs in Pharmacology
PharmacologyGeneral
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Q55009.Β Which of the following terms best describes a drug that blocks the action of epinephrine at its receptors by occupying those receptors without activating them ?

A.Pharmacological antagonist
B.Partial agonist
C.Physiological antagonist
D.Chemical antagonist

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MCQs in Pharmacology
PharmacologyGeneral
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Q55010.Β Which of the following provides information about the variation in sensitivity of the drug within the population studied ?

A.Maximal efficacy
B.Therapeutic index
C.Drug potency
D.Grade dose-response curve

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MCQs in Pharmacology
PharmacologyGeneral
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Q55011.Β Which of the following most accurately describes the transmembrane signaling process involved in steroid hormone action ?

A.Action on a membrane spanning tyrosine
B.Activation of a G protein which activates or
C.Diffusion into the cytoplasm and binding to
D.Diffusion of β€œSTAT” molecules across the

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MCQs in Pharmacology
PharmacologyGeneral
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Q55012.Β Which of the following is a phase II drug- metabolizing reaction ?

A.Acetylation
B.Deamination
C.Hydrolysis
D.Oxidation

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MCQs in PharmacologyGeneral
PharmacologyGeneral
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Q55013.Β Which of the following drugs may inhibit the hepatic microsomal P450 responsible for warfarin metabolism

A.Cimetidine
B.Ethanol
C.Phenobarbital
D.Procainamide

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MCQs in PharmacologyGeneral
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