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PathologyThyroid Tumors

Q33. A 50-year-old female presents with a firm thyroid swelling. FNAC reveals marked cellular pleomorphism with variation in cell size and shape. Histopathology shows amyloid deposition in the stroma. Immunohistochemistry is TTF-1 negative, positive for chromogranin and synaptophysin. Which of the following is the most likely diagnosis?

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NEET-PG2025Repeats: 2020, 2023
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