Q1434. Patient presents with progressive weakness of both upper and lower limbs for 8 months. He has muscle wasting of the hands, fasciculations, and brisk deep tendon reflexes. Plantar response is extensor. Sensory examination is normal. There is no bladder or bowel involvement. What is the most likely diagnosis?

Q1438. examination, there is a visibly strong, bounding pulsation in the neck with a prominent carotid upstroke. Careful inspection of the nail beds reveals rhythmic pulsatile blanching synchronous with the cardiac cycle. Which of the following auscultatory findings best corresponds to this clinical presentation?

Q1442. lifestyle measures. Laboratory evaluation reveals hypokalemia associated with metabolic alkalosis. There is no history of diuretic intake, and renal function tests are within normal limits. Which of the following is the most likely diagnosis?

Q1444. A patient is admitted with a head injury in the ER. On examination, he is having bradycardia with hypertension and posturing. You notice the following breathing pattern. Diagnosis is?

Q1449. of the left upper and lower limbs, slurred speech that started 2 hours ago while he was watching TV. There is no history of headache or loss of consciousness. He has a history of hypertension and type 2 diabetes for 10 years. Non-contrast CT brain is shown. Which of the following is the most appropriate initial management?

Q1488. A 32-year-old woman with a history of chronic hypertension seeks advice on contraception. She has no other significant medical issues. Which of the following contraceptive methods is contraindicated in her condition?

Q1524. A patient with long standing smoking history from years with COPD is planned for abdominal surgery. What is the most effective measure to reduce the risk of postoperative pulmonary complications?

Q1560. A 32-year-old woman presents with fatigue, low-grade fever, and dry cough for the past 2 months. She also has painful red nodules on her shins. ACE levels rasied. Chest X-ray given below . Which of the following is true about the stage of disease?

Q1567. A 10-year-old child presents with intense itching that worsens at night. There is a history of bronchial asthma. On examination, there are ill-defined, erythematous, excoriated plaques over the flexural areas. What is the most likely diagnosis?

Q1589. reveal megaloblastic anemia. Further metabolic testing shows elevated serum homocysteine and decreased plasma cysteine levels. Serum methylmalonic acid is normal. There are no neurological symptoms.Which of the following is the most likely cause of his condition?

Q1617. A patient with chronic kidney disease (CKD) presents with severe anemia. Laboratory tests reveal a normocytic normochromic anemia. What is the most appropriate treatment to manage this patient?

Q1622. A patient with chronic kidney disease, serum creatinine: 2.1 mg/dL, estimated GFR: 45 mL/min/1.73 m², 3+ proteinuria and blood pressure 148/92 mmHg is being evaluated for management. Which of the following is the most appropriate antihypertensive agent in this scenario?

Q1660. A person shifting from Nigeria to the USA should carry which vaccination certificate?

Q1752. ear-olo gentleman with normal renal functions presents with new onset focal seizures. Which of the following is the best drug to manage the patient?

Q1753. A 29-year-old, 4 months pregnant primigravida has history of juvenile myoclonic epilepsy. She has been regularly taking sodium valproate and now presents requesting for an opinion for a change in her anti-epileptic treatment: What would you sugeets her? Immediately taper off valproate and start lamotrigine

Q1754. Which of the following is used in the treatment of Multiple Sclerosis:

Q1755. All of the following are approved for the treatment of relapsing-remmitting multiple sclerosis (RRMS) subtype, except-

Q1757. Diabetes control is best monitored by:

Q1758. With reference to the optimal management of patients with sepsis in the intensive care unit; all of the following interventions are evidence- based except: