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PharmacologyCardiovascular Drugs
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Q5770. Specific inhibitor of succinate dehydrogenase?

A.Fluoroacetate
B.Arsenite
C.Malonate
D.Fluoride

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2014
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PharmacologyCardiovascular Drugs
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Q5802. Immediate precursor of creatine

A.Carbamoyl phosphate
B.Arginosuccinate
C.Guanidoacetate
D.Citrulline

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PharmacologyCardiovascular Drugs
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Q5807. Citrullinemia is due to deficiency of ?

A.Argininosuccinate lyase
B.Argininosuccinate synthase
C.Arginase
D.Ornithine transcarbamylase

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PharmacologyCardiovascular Drugs
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Q5850. Which of the following is a homopolysaccharide?

A.Heparin
B.Chitin
C.Hyaluronic acid
D.Chondroitin sulfate

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Q5974. Glucuronidation takes place in ?

A.Liver
B.RBC
C.Pancreas
D.Thyroid

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Q5982. Which of the following drug substrate combinations do not match ?

A.CYP 3A4/5 - simvastatin
B.CYP 2D6 - SSRI
C.CYP 2C8/9 - mifepristone
D.CYP 2C19 - propranolol

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Q6002. IV diazepam has which of the following effect which is not seen by other routes ?

A.Analgesia
B.Sedation
C.Hypotension
D.Coronary dilatation

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Q6008. Inverse agonist of benzodiazepine receptor is -

A.Phenobarbitone
B.Flumazenil
C.Beta carboline
D.Gabapentin

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Q6016. Natalizumab is used in treatment of ?

A.Muliple sclerosis
B.Breast carcinoma
C.Psoriasis
D.B cell lymphoma

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Q6022. Which does not act by blocking NMDA receptors?

A.Methoxetamine
B.Methadone
C.Ketamine
D.Diltiazem

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Q6026. Oxcarbazepine true is all except ?

A.Metabolises itself
B.Less chances of hyponatremia than carbazepine
C.It is less enzyme inducer than carbamazepine
D.Less chances of hepatotoxicity than carbamazepine

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Q6029. A = ACE inhibitor, B = beta blocker, C = calcium channel blocker, D= diuretics. For elderly with hypertension antihypertensive drug of choice is ?

A.A or D
B.A or B
C.A or C
D.C or D

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Q6057. Agent used for treatment of heparin induced thrombocytopenia ?

A.Lepirudin
B.Abciximab
C.Warfarin
D.Alteplase

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Q6063. Hypolipidemic drugs act on all except ?

A.HMG Co A reductase
B.Lipoprotein lipase
C.Acyl CoA, cholesterol acyl transferase 1
D.Peripheral decarboxylase

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Q6068. Drug not acting on P2y12 receptor is ?

A.Ticlopidine
B.Clopidrogel
C.Dipyridamole
D.Prasugrel

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Q6074. Which of the following is the longest acting oral anticoagulant ?

A.Bishydroxycoumarin
B.Warfarin
C.Acenocoumarol
D.Phenindione

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Q6076. Which of the following is a univalent direct thrombin inhibitor?

A.Argatroban
B.Hirudin
C.Bivalirudin
D.Lepirudin

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Q6080. Compared to high molecular weight heparin following is true about low molecular weight heparin ?

A.Monitoring is not needed for low molecular weight heparin
B.Daily two subcutaneous doses are essential
C.They are easily filtered at the glomerulus
D.They do not interact with plasma proteins

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Q6082. Which of the following is not an anti histaminic drug of the ethanolamine group?

A.Clemastine
B.Diphenhydramine
C.Dimenhydrinate
D.Chlorpheniramine

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Q6084. Heparin activates following factors except ?

A.IIa
B.VIIa
C.IXa
D.Xa

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