Q1067. Laxative abuse is associated with

Q1102. Enzyme replacement therapy is available for

Q1145. A 6 month old child started vomiting and ceased to gain weight. At 8 months, he had to be admitted to the hosipital. After one week, he started getting drowsy. He couldn’t tolerate feeding even by gastrostomy and had to be given intravenous glucose, following which he improved dramatically and came out of coma in 24 hours. Physical examination was normal, but his urine had high levels of glutamine and uracil, and increased levels of ammonia in blood. What is the enzyme defect he has?

Q1146. Lipolysis by which adrenoceptor

Q1153. Mr.X shot mr.Y with shotgun, but mr.Y got a small injury on thigh, and mild bleeding which stopped spontaneously. Bt still Mr.Y filed case against mr.X. What will be the IPC for penalty to Mr.X

Q1158. Characteristic marker of limbal epithelial cell

Q1319. A middle-aged man presents with photosensitivity, recurrent blistering lesions over sun-exposed areas, skin fragility, and hyperpigmentation. Laboratory evaluation reveals accumulation of uroporphyrins in urine. Which of the following enzymes is defective in this condition?

Q1330. In COPD destruction of alveolar elastin is mediated by which of the following enzymes?

Q1345. A female child is diagnosed with iron deficiency anemia and started on iron–folic acid tablets. The clinician also adds an additional vitamin to improve the efficacy of the therapy. Which regimen is most appropriately co-administered with iron–folic acid?

Q1347. A 65-year-old woman with breast cancer was given combination chemotherapy including methotrexate. To reduce toxicity, leucovorin is administered. Which of the following enzymes is bypassed by leucovorin rescue during methotrexate therapy?

Q1354. and telmisartan. She has an HbA1c level of 8.5. Her blood pressure is normal, and recent investigations show eGFR to be < 50 mL/min/1.73 m², but serum potassium is normal, and she is asymptomatic. What should be done to decrease the risk of further decrease in GFR?

Q1374. 23 A burnt body with suspected internal injuries is examined without performing a conventional dissection. What type of autopsy is done to evaluate fractures, internal hemorrhage, and organ injuries, while preserving the body intact?

Q1392. 27 5 year old child, brought to ENT OPD with complaints of cosmetic deformity in the external ear since birth. Hearing is normal. What is the best age to surgically correct this deformity?

Q1397. obstruction, foul smelling nasal discharge, crusting with hardened external nose and episodic epistaxis. On examination the nasal cavity shows pale, granular, nodular mass leading to obstruction. What is the treatment of choice for this condition?

Q1419. After 2024, according to the National Rural Health Mission reforms, this institute has been renamed and upgraded to provide comprehensive primary care including preventive, promotive, curative, and rehabilitative services. What is the current official name of this institute?

Q1426. Vitamin A is added to butter to prevent deficiency in the population. This is an example of

Q1437. retrosternal chest pain associated with diaphoresis and nausea. Electrocardiogram shows ST-segment elevation in leads II, III, and aVF. On examination, his blood pressure is 80/60 mmHg with cool extremities, but lung fields are clear on auscultation. What is the next best step in management?

Q1457. A patient undergoes liver surgery. Postoperatively, bilirubin levels remain elevated, despite treatment. Laboratory investigations show elevated direct bilirubin, but unconjugated bilirubin is normal, and there is no increase in urobilinogen in urine. Which of the following is primarily responsible for the elevated bilirubin?

Q1471. epigastric pain radiating to the back, significant weight loss, and steatorrhea for the past 1 year. Investigations show elevated pancreatic enzymes, pancreatic calcifications on CT. There is no pancreatic head mass, no biliary obstruction, and no suspicion of malignancy. What is the most appropriate initial management for this patient?