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PharmacologyAntimicrobials
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Q13432. Sulphonamide injection causes decrease in folic acid by?

A.Competitive inhibition
B.Non competitive inhibition
C.Uncompetitive inhibition
D.Allosteric inhibition

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Q13433. All are true about ciprofloxacin except ?

A.C/I in pregnancy
B.DNA inhibition
C.Most potent 1st generation fluoroquinolone
D.More active at acidic pH

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Q13436. Widest spectrum aminoglycoside is -

A.Streptomycin
B.Amikacin
C.Framycetin
D.Netilmicin

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Q13440. Which of the following antimalarial is a slow acting schizonticide-

A.Artemether
B.Mefloquine
C.Pyrimethamine
D.Quinine

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Q13442. Drug that can cause hypertrophic pyloric stenosis is?

A.Tertacyclin
B.Erythromycin
C.Ampicillin
D.Rifampicin

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Q13449. Intracranial pressure may be increased by all of the following drugs except -

A.Hypervitaminosis A
B.Corticosteroids
C.Quinolones
D.Aminoglycosides

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Q13452. Which of the following drugs is associated with untoward side effect of renal tubular damage-

A.Cisplatin
B.Steptozotocin
C.Methysergide
D.Cyclophosphamide

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Q13467. Cyclic peptide chain is present in ?

A.Gramicidin A
B.Gramicidin B
C.Gramicidin D
D.Gramicidin S

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Q13470. Anticancer drug with disulfuram like action -

A.Procarbazine
B.Nitrosurea
C.5 FU
D.Methotrexate

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Q13489. Irreversible hearing loss caused by ?

A.Gentamycin
B.Clarithromycin
C.Both of the above
D.None of the above

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Q13492. Drug of choice for MRSA infection ?

A.Ciprofloxacin
B.Oxacillin
C.Vancomycin
D.Clindamycin

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Q13498. Which anti TB drug is avoided in HIV patient ?

A.INH
B.Rifampicin
C.Pyrazinamide
D.Streptomycin

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Q13506. Mechanism of action of actinomycin D is ?

A.Inhibits DNA dependent RNA synthesis
B.Activates DNA dependent RNA synthesis
C.Inhibits RNA dependent DNA synthesis
D.Activates RNA dependent DNA synthesis

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Q13516. Colistin is obtained from ?

A.Bacteria
B.Fungi
C.Actinmycetes
D.Herbs

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Q13529. Treatment agent for scarlet fever is

A.Penicillin
B.Ciprofloxacin
C.Erythromycin
D.Chloramphenicol

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Q13561. Antifungal which can be used orally but not iv is?

A.Voriconazole
B.Amphoterecin B
C.Terbinafine
D.None of the above

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Q13562. Mechanism of action tacrolimus is ?

A.Inhibition of calcineurin
B.Antimetabolite
C.mTOR inhibitor
D.Inhibition of DNA synthesis

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Q13569. Fluoroquinolone with minimum bioavailability ?

A.Levofloxacin
B.Moxifloxacin
C.Norfloxacin
D.Ciprofloxacin

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Q13576. Cephalosporin causing thrombocytopenia is ?

A.Cefixime
B.Ceftazidime
C.Cefoperazone
D.Cefdinir

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Q13585. All of the following can precipitate porphyria except ?

A.Steroids
B.Griesiofulvin
C.Penicillin
D.Estrogen

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