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Q7887. Immediate source of energy is ?

A.Cori's cycle
B.HMP
C.ATP
D.TCA cycle

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Q7946. Most important tool used in genetic engineering

A.Halicase
B.Topoisomerase
C.DNA Ligase
D.Restriction endonuclease

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Q7964. Not an irreversible injury-

A.Pyknosis
B.Pyknosis
C.Karyolysis
D.Bleb formation

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Q7965. Hypertrophy is -

A.Increase in cell number
B.Increase in cell size
C.Decrease in cell number
D.Decrease in cell size

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Q7969. In cell death, myelin figures, are derived from-

A.Nucleus
B.Cell membrane
C.Cytoplasm
D.Mitochondria

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Q7970. Lipofuscin is

A.Wear and tear pigment
B.Fat deposits
C.Blood pigment
D.Form of calcification

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Q8003. Organ with least chance of rejection

A.Blood
B.Kidney
C.Heart
D.Liver

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Q8021. Level of which of the following is not elevated in heart disease

A.LDH
B.5-nucleotidase
C.SGOT
D.ALP

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Q8023. Lines of Zahn are seen in -

A.Heart
B.Lung
C.Liver
D.Kidney

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Q8042. Following are seen in polycythemia vera except:

A.Most common cause of polycythemia
B.Increased erythropoietin
C.Erythropoietin independent growth of red cell progenitors
D.Intrinsic abnormality of hematopoietic precursors

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Q8064. The predominant isozyme of LDH in Lung is:

A.LD-1
B.LD-2
C.LD-3
D.LD-5

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Q8076. Solution currently used for liver preservation for transplant is -

A.UW solution
B.IGL solution
C.Kyoto ET solution
D.Ross Marshal Citrate solution

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Q8091. True about drug metabolism ?

A.Glucuronidation is phase I reaction
B.Most common enzyme involved is Cyp 3A4/5
C.Reduction is most common reaction
D.Cytochrome p450 is involved phase-II reaction

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Q8115. True about cardiac muscle fibers ?

A.Digitalis decreases force of contraction
B.Na+ - Ca+ exchanger requires ATP directly
C.Na+-Ca+ exchanger acts to pump Ca2+ into heart muscle cells
D.All are true

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Q8120. Drug affecting positive free water clearance without affecting negative free water clearance -

A.Loop diuretics
B.Thiazides
C.Acetazolamide
D.Amiloride

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Q8123. Sympathomimetic drug which causes decrease in heart rate ?

A.Adrenaline
B.Isoprenaline
C.Noradrenaline
D.None

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Q8124. Following are the side effects of thiazides except?

A.Hypokalemia
B.Hypocalcemia
C.Hepatic coma
D.Impotence

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Q8143. A 47-year-old woman presents with complaints of nervousness and increased sensitivity to hot weather. She is diagnosed with hyperthyroidism and prescribed propylthiouracil. What is the principal mechanism by which this drug acts?

A.Decreasing the efficacy of TSH binding to the thyroid TSH
B.Decreasing the rate of proteolysis of thyroglobulin
C.Increasing the amount of 3,3',5'-triiodothyronine (reverse T3;
D.Inhibiting deiodination of thyroxine (T4)

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Q8170. Antitubercular drug which makes the patient non-infective earliest ?

A.INH
B.Rifampin
C.Ethambutol
D.Pyrazinamide

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Q8201. IPC 304B is related to -

A.Punishment for cruelty by husband or his relatives
B.Dowry death
C.Death caused by negligence
D.Punishment of culpable homicide, not amounting to murder

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