Q1604. The tumor suppressor protein p53 promotes apoptosis by increasing the expression of which of the following pro-apoptotic genes?
Premium Question
Unlock to see the answer & explanation
Q1605. Marfan syndrome is caused by mutations in which of the following genes?
Premium Question
Unlock to see the answer & explanation
Q1607. Bernard-Soulier syndrome is caused by a defect in which of the following platelet glycoproteins?
Premium Question
Unlock to see the answer & explanation
Q1609. A newborn presents with hypotonia, upward slanting palpebral fissures, a round facial profile, flat nasal bridge, and curved small fingers. What is the most likely diagnosis?
Premium Question
Unlock to see the answer & explanation
Q1610. and gradually worsening renal dysfunction. He now has proteinuria and signs of nephrotic syndrome. A renal biopsy is performed. On Congo red staining, amorphous eosinophilic deposits are seen, which show apple green birefringence under polarized light.What is the most likely diagnosis?
Premium Question
Unlock to see the answer & explanation
Q1612. In pap smear, which of the following is the most appropriate fixative used to preserve cellular details after smearing?
Premium Question
Unlock to see the answer & explanation
Q1613. A young boy presents with joint swelling after a minor fall. Laboratory investigations show prolonged aPTT with normal BT and PT. What is the most likely diagnosis?
Premium Question
Unlock to see the answer & explanation
Q1615. For testing blood coagulation studies, blood is collected in which color coded vacutainer tube?
Premium Question
Unlock to see the answer & explanation
Q1617. A patient with chronic kidney disease (CKD) presents with severe anemia. Laboratory tests reveal a normocytic normochromic anemia. What is the most appropriate treatment to manage this patient?
Premium Question
Unlock to see the answer & explanation
Q1619. Which of the following is used as an abortive treatment for cluster headcahes?
Premium Question
Unlock to see the answer & explanation
Q1620. A 28-year-old male presents with excessive thirst and polyuria (~6–7 liters/day). He reports a history of head trauma one month ago. Laboratory tests reveal hypernatremia and low urine osmolality. What is the most appropriat pharmacological treatment?
Premium Question
Unlock to see the answer & explanation
Q1622. A patient with chronic kidney disease, serum creatinine: 2.1 mg/dL, estimated GFR: 45 mL/min/1.73 m², 3+ proteinuria and blood pressure 148/92 mmHg is being evaluated for management. Which of the following is the most appropriate antihypertensive agent in this scenario?
Premium Question
Unlock to see the answer & explanation
Q1623. A known case of rheumatic heart disease is found to have a 1–2 cm coronary artery aneurysm on imaging. There are no signs of acute infection. What is the most appropriate pharmacological intervention?
Premium Question
Unlock to see the answer & explanation
Q1624. Which of the following is a correct drug regimen for the treatment of Helicobacter pylori infection?
Premium Question
Unlock to see the answer & explanation
Q1627. A pregnant woman presents with headache and decreased vision. MRI reveals a pituitary macroadenoma compressing the optic chiasma. What is the drug of choice to manage this patient?
Premium Question
Unlock to see the answer & explanation
Q1630. A patient with allergic rhinitis has been taking cetirizine but reports experiencing excessive sedation. Which of the following antihistamines would be the best alternative with minimal sedative effects?
Premium Question
Unlock to see the answer & explanation
Q1636. Which of the following cancers is not protected against by the use of OCPs?
Premium Question
Unlock to see the answer & explanation
Q1637. MICRO A 5-year-old child is diagnosed with pneumonia after presenting with fever, cough, and difficulty breathing. Laboratory tests confirm the presence of an influenza virus infection. Based on the properties of the virus, identify the correct statement?
Premium Question
Unlock to see the answer & explanation
Q1639. breathing. A throat swab is sent for culture. On chocolate agar, the organism shows growth with no hemolysis. Gram stain reveals small gram-negative coccobacilli. Which of the following organisms is most likely being isolated on chocolate agar?
Premium Question
Unlock to see the answer & explanation
Q1640. lymphadenopathy. Laboratory tests reveal elevated liver enzymes, thrombocytopenia, and a normal white blood cell count. Blood cultures are repeatedly negative. Which of the following organisms is the most likely cause of his illness?
Premium Question
Unlock to see the answer & explanation