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PathologyGeneral Pathology
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Q1604. The tumor suppressor protein p53 promotes apoptosis by increasing the expression of which of the following pro-apoptotic genes?

A.Bax
B.Bcl-2
C.Bcl-xL
D.Mcl-1

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FMGE
2025
Repeats: N/A
BiochemistryNucleotide Metabolism
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Q1605. Marfan syndrome is caused by mutations in which of the following genes?

A.Fibrillin-1
B.Collagen type I
C.Elastin
D.Laminin

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FMGE2025Repeats: N/A
BiochemistryMolecular Biology
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Q1607. Bernard-Soulier syndrome is caused by a defect in which of the following platelet glycoproteins?

A.Von Hippel–Lindau disease
B.Tuberous sclerosis
C.Multiple endocrine neoplasia type 1
D.Neurofibromatosis type 1

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FMGE2025Repeats: N/A
PaediatricsNeonatology
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Q1609. A newborn presents with hypotonia, upward slanting palpebral fissures, a round facial profile, flat nasal bridge, and curved small fingers. What is the most likely diagnosis?

A.Cri du chat syndrome
B.Patau syndrome
C.Down syndrome
D.Edward syndrome

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FMGE2025Repeats: N/A
MicrobiologyVirology
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Q1610. and gradually worsening renal dysfunction. He now has proteinuria and signs of nephrotic syndrome. A renal biopsy is performed. On Congo red staining, amorphous eosinophilic deposits are seen, which show apple green birefringence under polarized light.What is the most likely diagnosis?

A.CD19+, CD5+, CD23+, CD3+
B.CD19+, CD5+, CD10+, CD3+
C.CD20+, CD3+, CD5+, CD23+
D.CD3+, CD4+, CD19+, CD23+

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FMGE2025Repeats: N/A
ENTEar
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Q1612. In pap smear, which of the following is the most appropriate fixative used to preserve cellular details after smearing?

A.50% formaldehyde
B.95% ethyl alcohol
C.70% ethanol
D.10% buffered formalin

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FMGE2025Repeats: N/A
PathologyHematopathology
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Q1613. A young boy presents with joint swelling after a minor fall. Laboratory investigations show prolonged aPTT with normal BT and PT. What is the most likely diagnosis?

A.Von Willebrand disease
B.Hemophilia
C.Hers disease
D.Immune thrombocytopenic purpura

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FMGE2025Repeats: N/A
RadiologyGeneral Radiology
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Q1615. For testing blood coagulation studies, blood is collected in which color coded vacutainer tube?

A.Red top tube
B.Green top tube
C.Blue top tube
D.Gray top tube

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FMGE2025Repeats: N/A
MedicineNephrology
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Q1617. A patient with chronic kidney disease (CKD) presents with severe anemia. Laboratory tests reveal a normocytic normochromic anemia. What is the most appropriate treatment to manage this patient?

A.Folic acid supplementation
B.Darbepoetin alfa
C.Granulocyte colony-stimulating factor
D.Romiplastim

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FMGE2025Repeats: N/A
PharmacologyAutonomic Pharmacology
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Q1619. Which of the following is used as an abortive treatment for cluster headcahes?

A.Oxygen
B.Verapamil
C.Propranolol
D.Topiramate

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BiochemistryMolecular Biology
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Q1620. A 28-year-old male presents with excessive thirst and polyuria (~6–7 liters/day). He reports a history of head trauma one month ago. Laboratory tests reveal hypernatremia and low urine osmolality. What is the most appropriat pharmacological treatment?

A.Ibuprofen
B.Diclofenac
C.Naloxone
D.

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FMGE2025Repeats: N/A
MedicineNephrology
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Q1622. A patient with chronic kidney disease, serum creatinine: 2.1 mg/dL, estimated GFR: 45 mL/min/1.73 m², 3+ proteinuria and blood pressure 148/92 mmHg is being evaluated for management. Which of the following is the most appropriate antihypertensive agent in this scenario?

A.Aspirin lifelong
B.Aspirin + Clopidogrel
C.Amlodipine
D.Metoprolol

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FMGE2025Repeats: N/A
AnatomyThorax
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Q1623. A known case of rheumatic heart disease is found to have a 1–2 cm coronary artery aneurysm on imaging. There are no signs of acute infection. What is the most appropriate pharmacological intervention?

A.Aspirin lifelong
B.Aspirin + Clopidogrel
C.Aspirin for 6 weeks
D.Aspirin + Steroids

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FMGE2025Repeats: N/A
PharmacologyAntimicrobials
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Q1624. Which of the following is a correct drug regimen for the treatment of Helicobacter pylori infection?

A.Metronidazole + Omeprazole + Amoxicillin
B.Metronidazole + Ciprofloxacin + Amoxicillin
C.Omeprazole + Amoxicillin + Clarithromycin
D.Omeprazole + Clarithromycin + Metronidazole

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FMGE2025Repeats: N/A
PharmacologyCNS Pharmacology
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Q1627. A pregnant woman presents with headache and decreased vision. MRI reveals a pituitary macroadenoma compressing the optic chiasma. What is the drug of choice to manage this patient?

A.Bromocriptine
B.Octreotide
C.Surgical decompression immediately
D.Expectant management

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FMGE2025Repeats: N/A
BiochemistryProtein & Amino Acid Metabolism
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Q1630. A patient with allergic rhinitis has been taking cetirizine but reports experiencing excessive sedation. Which of the following antihistamines would be the best alternative with minimal sedative effects?

A.Hydroxyzine
B.Diphenhydramine
C.Fexofenadine
D.Promethazine

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FMGE2025Repeats: N/A
PathologyOncology
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Q1636. Which of the following cancers is not protected against by the use of OCPs?

A.Colorectal cancer
B.Cervical carcinoma
C.Endometrial carcinoma
D.Ovarian carcinoma

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ENTEar
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Q1637. MICRO A 5-year-old child is diagnosed with pneumonia after presenting with fever, cough, and difficulty breathing. Laboratory tests confirm the presence of an influenza virus infection. Based on the properties of the virus, identify the correct statement?

A.Non enveloped, ssRNA virus
B.Enveloped, dsRNA virus
C.Non-enveloped, dsRNA virus
D.Enveloped, ssRNA virus

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FMGE2025Repeats: N/A
MicrobiologyBacteriology
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Q1639. breathing. A throat swab is sent for culture. On chocolate agar, the organism shows growth with no hemolysis. Gram stain reveals small gram-negative coccobacilli. Which of the following organisms is most likely being isolated on chocolate agar?

A.Haemophilus influenzae
B.Listeria monocytogenes
C.Streptococcus pneumoniae
D.Escherichia coli

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FMGE2025Repeats: N/A
BiochemistryProtein & Enzyme Metabolism
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Q1640. lymphadenopathy. Laboratory tests reveal elevated liver enzymes, thrombocytopenia, and a normal white blood cell count. Blood cultures are repeatedly negative. Which of the following organisms is the most likely cause of his illness?

A.Coxiella burnetii
B.Rickettsia rickettsia
C.Rickettsia typhi
D.Brucella melitensis

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FMGE2025Repeats: N/A
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