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Q5789. Which of the following is the rate limiting step in cholesterol synthesis?

A.HMG CoA synthase
B.HMG CoA reductase
C.Thiokinase
D.Mevalonate kinase

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2011
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PsychiatryMood Disorders
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Q5804. Bond involved in formation of primary structure of protein/polypeptide ?

A.Hydrogen
B.Peptide
C.Disulfide
D.a and b both

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Q5836. Northern blot is used to detect ?

A.Protein
B.Immunoglobulin
C.RNA
D.DNA

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Q5849. Strongest interactions among the following

A.Covalent
B.Hydrogen
C.Electrostatic
D.Van der Waals

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Q5852. Following is true regarding sulhydryl groups except?

A.They are present in coenzyme A and lipoic acid
B.They are present in Captopril and penicillamine
C.They are not involved in reduction of peroxides
D.They are present in cysteine

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Q5863. The Fenton reaction leads to free radical generation when:

A.Radiant energy is absorbed by water
B.Ferrous ions are converted to ferric ions
C.Nitric oxide is converted to peroxynitrite anion
D.Hydrogen peroxide is formed by, myeloperoxidase

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Q5868. Leukocyte adhesion to endothelium is mediated by all except ?

A.L selectin
B.E selectin
C.VCAM 1
D.VCAM 4

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Q5869. Endothelial molecule participating in rolling is

A.CD 34
B.CD 65
C.CD 56
D.CD 100

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Q5879. Macrophage activation syndrome characterized by all except ?

A.Activation of CD 8 + T cells
B.Presence of cytokine storm
C.It is the other name for hemophagocytic lymphohistiocytosis
D.Low levels of plasma ferretin

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Q5885. NK cell shows presence of ?

A.CD 44
B.CD 16
C.CD 54
D.CD 32

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Q5889. Hyperimmune IgE syndrome is also called

A.Jobs syndrome
B.Wiscott Aldrich syndrome
C.Chediak-Higashi syndrome
D.Digeorge syndrome

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Q5891. Leukocyte migration through endothelium is induced by ?

A.Selectin
B.N CAM
C.C CAM
D.PECAM

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Q5909. Boys are more likely to be affected by which genetic disorders ?

A.AD
B.AR
C.X linked dominant
D.X linked recessive

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Q5944. Carcinoid syndrome produces valvular disease primarily of the

A.Venous valves
B.Tricuspid valve
C.Mitral valve
D.Aortic valve

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Q5957. Defect of glanzmann's thrombosthenia is ?

A.Gp1Ib-IlIa
B.GpIIIa-I lb
C.GpIla-Illb
D.Gpfilb-I la

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Q5958. Giant platelets are seen in ?

A.Bernard soulier syndrome
B.vWD
C.Polycythemia rubra vera
D.Leukemia

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Q5961. Following statement is true for hemophilia patients?

A.All Females are carriers and all males are affected
B.All Males are carriers and all females are affected
C.Females are mostly carriers and all males are affected
D.Males are mostly carriers and all females are affected

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Q5966. Depot preparations are administered by ?

A.Subcutaneous route
B.Intravenous route
C.Intramuscular route
D.Both subcutaneous and intramuscular route

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Q5967. Most variable absorption is seen with which route?

A.Oral
B.Intramscular
C.Intravenous
D.Per rectal

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Q5968. About rectal route true is ?

A.Used for irritant and unpleasant drugs
B.Cannot be used in unconscious patient
C.There is predictable absorption of drug
D.Diazepam cannot be given via rectal route of administration

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