Q1426. Vitamin A is added to butter to prevent deficiency in the population. This is an example of

Q1437. retrosternal chest pain associated with diaphoresis and nausea. Electrocardiogram shows ST-segment elevation in leads II, III, and aVF. On examination, his blood pressure is 80/60 mmHg with cool extremities, but lung fields are clear on auscultation. What is the next best step in management?

Q1457. A patient undergoes liver surgery. Postoperatively, bilirubin levels remain elevated, despite treatment. Laboratory investigations show elevated direct bilirubin, but unconjugated bilirubin is normal, and there is no increase in urobilinogen in urine. Which of the following is primarily responsible for the elevated bilirubin?

Q1471. epigastric pain radiating to the back, significant weight loss, and steatorrhea for the past 1 year. Investigations show elevated pancreatic enzymes, pancreatic calcifications on CT. There is no pancreatic head mass, no biliary obstruction, and no suspicion of malignancy. What is the most appropriate initial management for this patient?

Q1474. A patient involved in a road traffic accident presents with a crush injury to the limb. Based on disaster triage principles, what is the appropriate triage category?

Q1477. A 55-year-old man presents to the emergency department with sudden severe retrosternal chest pain and retching/vomiting after a heavy meal and alcohol intake. On examination, he is tachycardic, hypotensive, and has subcutaneous emphysema over the neck and upper chest. What is the most appropriate next step in diagnosis?

Q1509. A 28-year-old woman, 28 weeks pregnant, comes for a routine checkup. She feels well. On examination, a soft, early mid-systolic murmur is heard at the left sternal border. There are no thrills, heaves, or other abnormal findings. What is the most likely cause?

Q1516. A 6-month-old infant presents with bleeding gums, easy bruising, and recurrent diarrhea. Growth is otherwise normal. Which of the following vitamin deficiencies is most likely?

Q1532. A 30-year-old male is admitted after a motor vehicle accident, where his knees hit the dashboard. He complains of severe pain in the right hip, inability to move the leg, and the limb appears shortened and internally rotated. A pelvic X-ray is performed. What is the most likely diagnosis?

Q1575. Which Vitamin deficiency can cause lactic acidosis?

Q1580. In malignant hyperthermia, a genetic mutation in the ryanodine receptor (RYR1) leads to a life-threatening reaction to certain anesthetic agents. What is the primary ionic abnormality caused by this receptor defect?

Q1582. A man presents with elevated VLDL and chylomicrons, along with eruptive xanthomas. What is the most likely diagnosis?

Q1583. A breastfed infant presents with lethargy, hepatomegaly, and cataracts. Which enzyme deficiency is most likely responsible for this presentation?

Q1585. A family consumes a diet predominantly composed of rice and pulses and has developed signs of muscle weakness and movement issues. Which of the following supplements should be given prophylactically?

Q1586. Which of the following acts as a major intracellular antioxidant and helps detoxify reactive oxygen species?

Q1588. A 2-month-old infant presents with poor feeding, vomiting, and lethargy. Laboratory studies reveal hyperammonemia and elevated levels of orotic acid in the urine. Which enzyme deficiency is most likely?

Q1605. Marfan syndrome is caused by mutations in which of the following genes?

Q1607. Bernard-Soulier syndrome is caused by a defect in which of the following platelet glycoproteins?

Q1620. A 28-year-old male presents with excessive thirst and polyuria (~6–7 liters/day). He reports a history of head trauma one month ago. Laboratory tests reveal hypernatremia and low urine osmolality. What is the most appropriat pharmacological treatment?