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BiochemistryCarbohydrate Metabolism
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Q9538. All of the following are true about lactate utilisation in liver except -

A.Total net number of ATP formed because of cori's cycle is
B.Cori's cycle shifts the metabolic burden from muscle to liver
C.Cori's cycle can not be sustained indefinitely because it is
D.Cori's cycle is linked to glycogen synthesis in muscle

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BiochemistryCarbohydrate Metabolism
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Q9539. Which of the following is true about effect of insulin and glucagon on gluconeogenesis?

A.Insulin favours the formation of fructose 2,6 bisphosphate
B.Fructose 2, 6 bisphosphate is an inhibitor of glycolysis
C.Insulin acts through a kinase
D.Glucagon stimulates PFK.2 activity of the tandem enzyme

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BiochemistryCarbohydrate Metabolism
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Q9540. Key enzyme of gluconeogenesis are all except?

A.Pyruvate carboxylase
B.PEP carboxykinase
C.Pyruvate kinase
D.Glucose-6-phosphatase

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BiochemistryCarbohydrate Metabolism
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Q9541. In glycogen synthesis the active form of glucose used is-

A.Glucose 6 phosphate
B.Glucose I phosphate
C.UDP glucose
D.UTP glucose

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BiochemistryCarbohydrate Metabolism
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Q9542. UDP glucose is not used in ?

A.Uronic acid pathway
B.Glycogen synthesis
C.Galactose metabolism
D.HMP shunt

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Q9543. Neonatal hypoglycaemia which does not respond to counter regulatory hormone administration is diagnostic of -

A.Her's disease
B.Cori's disease
C.Anderson's disease
D.Von Gierke's disease

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BiochemistryLipid Metabolism
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Q9546. Which of the following is a transfatty acid?

A.Oleic acid
B.Elaidic acid
C.Stearic acid
D.Arachidonic acid

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Q9548. Arachidonic acid oxidation involves how many cycles of beta oxidation?

A.l0
B.20
C.9
D.8

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BiochemistryLipid Metabolism
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Q9549. All are true about beta oxidation of fatty acids except -

A.Carnitine acyl transferase I is the rate limiting enzyme of
B.Carnitine acyl transferase I is stimulated by Acyl CoA
C.Carnitine Acyl transferase I is stimulated by malonyl CoA
D.Carnitine Acyl transferase I defect causes a decrease in

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BiochemistryLipid Metabolism
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Q9551. Which of the following is true about Beta oxidation of fatty acids?

A.Stearic acid on oxidation provides 106 ATPs
B.Odd chain fatty acid oxidation provides only propionyl coA
C.Fatty acid oxidation defects cause hypoglycemia
D.Ketone bodies are formed by incomplete oxidation of fatty

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Q9552. Which of the following is true about properties of VLDL/LDL-

A.In electrophoresis, VLDL migrates more cathodal than LDL
B.LDL is formed from liver
C.LDL is formed from Chylomicron
D.VLDL remnants reach extrahepatic tissues

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BiochemistryLipid Metabolism
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Q9553. Reverse cholesterol transport - all are true except-

A.Transport of cholesterol from extrahepatic tissues to liver
B.ATP Binding Cassette Transporter protein is involved in the
C.Lecithin Cholesterol Acyl Transferase helps in the
D.Cholesterol Ester Transfer Protein helps in increasing HDL

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BiochemistryLipid Metabolism
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Q9554. Progesterone synthesis requires -

A.LDL
B.VLDL
C.HDL
D.Chylomicron

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Q9555. Site of small chain fatty acid absorption is -

A.Ileum
B.Duodenum
C.Ascending colon
D.Rectum

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Q9556. HMG CoA is precursor of all except-

A.Ubiquinone
B.Dolichol
C.Bile pigments
D.Ketone body

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Q9557. Refsum's disease is due to deficiency of which of the following enzyme?

A.Malonate dehydrogease
B.Thiophorase
C.Succinate thiokinase
D.Phytanic alpha oxidase

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BiochemistryLipid Metabolism
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Q9559. All are true about ketone bodies except ?

A.Acetoacetate is primary ketone body
B.Synthesized in mitochondria
C.Synthesized in liver
D.HMG CoA reductase is the rate-limiting enzyme

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BiochemistryProtein & Amino Acid Metabolism
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Q9561. Amino acid in synthesis of neurotransmitter

A.Glutamate
B.Proline
C.Cysteine
D.Alanine

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BiochemistryProtein & Amino Acid
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Q9563. Essential amino-acid deficiency affect nitrogen balance by

A.Increasing protein degradation
B.Decreasing protein degradation
C.Decreasing protein synthesis
D.Increasing protein synthesis

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Q9564. Creatinine is formed from :

A.Arginine
B.Lysine
C.Leucine
D.Histamine

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