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PharmacologyCardiovascular Drugs
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Q13757. Carbapenem which has tendency to cause maximum seizures?

A.Imipenem
B.Ertapenem
C.Doripenem
D.Meropenem

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PharmacologyCardiovascular Drugs
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Q13771. Which of the following drugs is not an inhibitor of P - glycoprotein?

A.Quinidine
B.Erythromycin
C.Verapamil
D.Phenobarbitone

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Q13774. Synergestic action is shown by the following drug combinations except?

A.Glibenclamide and metformin
B.Enalapril and hydrochlorthiazide
C.Levodopa and carbidopa
D.Hydrochlorthiazide and triamterene

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Q13781. Which of the following is an example of irreversible carbamate?

A.Ambenonium
B.Galantamine
C.Propoxur
D.Rivastigmine

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Q13782. 38 yr old patient with high risk of coronary artery disease risk has hypertention, which of the following antihypertensive drugs will be suitable as a first line treatment for this patient?

A.ACE inhibitors
B.Calcium channel blockers
C.Beta adrenergic blockers
D.Diuretics

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Q13784. A side effect of loop diuretics is used in ?

A.Post - surgery care
B.Chronic anemia
C.Blood transfusion
D.Oncology/cancer

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Q13787. Which of the following antiarrhythmic drugs can develop Long QT syndrome?

A.Ibutilide
B.Dofetilide
C.Sotalol
D.All the above

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Q13788. Which of the following is not true about the mechanism of action of digitalis?

A.It binds to the intracellular face of Na' ATPase enzyme
B.There is rise in intracellular Na'
C.It has positive ionotropic action
D.Digitalis action is independent of cardiac innervation

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Q13792. Rasburicase is an analogue of ?

A.Xanthine oxidase
B.IMP dehydrogenase
C.Adenosine Deaminase
D.Urate Oxidase

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Q13795. Use of PGF 2 a analogues is contraindicated in ?

A.Post partum harmorrhage
B.Glaucoma
C.Bronchial asthma
D.Priapism

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Q13800. Which of the following antithyroid medications had the maximum chances of causing agranulocytosis?

A.Carbimazole
B.Clotrimazole
C.Propylthiouracil
D.Methimazole

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Q13802. Pegvisomant is ?

A.Somatostatin antagonist
B.Somatotropin antagonist
C.GH receptor antagonist
D.GH receptor agonist

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Q13807. Mechanism of action of Voglibose is :?

A.p galactosidase inhibitor
B.3 lactase inhibitor
C.a glucosidase inhibitor
D.3 glucosidase inhibitor

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Q13810. All of the following are uses of octreotide except :?

A.Secretory diarrhea
B.Acromegaly
C.Hepatic encephalopathy
D.Bleeding esophageal varices

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Q13812. Mechanism of action of sulfonylureas is ?

A.Na ATP channel blocker
B.K ATP channel blocker
C.CI ATP channel blocker
D.Ca ATP channel blocker

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Q13815. Which of the following drugs halts macrovascular as well as microvascular effects of DM?

A.Acarbose
B.Biguanides
C.Meglitinide
D.Algaliptin

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Q13818. All of the following pairs are correct except ?

A.Peripheral decarboxylase inhibitor - Benserazide
B.MAO - B inhibitor - Clorgyline
C.COMT inhibitor - Entacapone
D.Dopamine facilitation - Amantadine

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Q13819. Which of the following is used for the patient on anti​parkinsonian medication levodopa + carbidopa, but patient showing marked on - off effect?

A.Bromocriptine
B.Amatidine
C.Selegeline
D.Rimonabant

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Q13820. Which of the following is not true about benzodiazepines?

A.Can produce ataxia
B.Has GABA facilitatory but no GABA mimetic action
C.REM, and Stage 3 and 4 sleep is increased
D.Produces muscle relaxation by action on medulla

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Q13821. Which of the following is not true about barbiturate?

A.Shows GABA mimetic action
B.Shows GABA facilitatory action
C.It can depress voltage gated Na.- and IC' channels at high
D.Limbic system is most sensitive to the depressive action of

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