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PharmacologyCardiovascular Drugs
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Q13540. Following are the side effects of thiazides except?

A.Hypokalemia
B.Hypocalcemia
C.Hepatic coma
D.Impotence

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Q13545. A = ACE inhibitor, B = beta blocker, C = calcium channel blocker, D= diuretics. For elderly with hypertension antihypertensive drug of choice is ?

A.A or D
B.A or B
C.A or C
D.C or D

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Q13559. Glucuronidation takes place in ?

A.Liver
B.RBC
C.Pancreas
D.Thyroid

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Q13560. Digitalis produces which of the following changes in ECG ?

A.Tall T waves
B.ST segment elevation
C.Prolonged QT interval
D.Prolonged PR interval

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Q13565. Adrenocortical suppression causing drugs are all except ?

A.Prednisone
B.Ketoconazole
C.Mitotane
D.Spironolactone

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Q13574. Compared to high molecular weight heparin following is true about low molecular weight heparin ?

A.Monitoring is not needed for low molecular weight heparin
B.Daily two subcutaneous doses are essential
C.They are easily filtered at the glomerulus
D.They do not interact with plasma proteins

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Q13579. Which of the following drug substrate combinations do not match ?

A.CYP 3A4/5 - simvastatin
B.CYP 2D6 - SSRI
C.CYP 2C8/9 - mifepristone
D.CYP 2C19 - propranolol

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Q13584. Which of the following is not an anti histaminic drug of the ethanolamine group?

A.Clemastine
B.Diphenhydramine
C.Dimenhydrinate
D.Chlorpheniramine

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Q13592. Oxcarbazepine true is all except ?

A.Metabolises itself
B.Less chances of hyponatremia than carbazepine
C.It is less enzyme inducer than carbamazepine
D.Less chances of hepatotoxicity than carbamazepine

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Q13593. Heparin activates following factors except ?

A.IIa
B.VIIa
C.IXa
D.Xa

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Q13595. Fastest acting antithyroid drugs ?

A.Iodides of Na/ K
B.Propylthiuracil
C.Methimazole
D.Nitrates

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Q13596. Natalizumab is used in treatment of ?

A.Muliple sclerosis
B.Breast carcinoma
C.Psoriasis
D.B cell lymphoma

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Q13600. Why quinine is unsafe in pregnancy?

A.It causes hemolysis
B.It causes hypokalemia
C.It causes hyponatremia
D.It causes smooth muscle contraction

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Q13602. Which does not act by blocking NMDA receptors?

A.Methoxetamine
B.Methadone
C.Ketamine
D.Diltiazem

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Q13607. Antihypertensive which can not be given in pregnancy ?

A.Labetolol
B.Propranolol
C.Esmolol
D.Hydralazine

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Q13618. Parenteral direct thrombin inhibitor ?

A.Ximelagatran
B.Dabigatran
C.Argatroban
D.Heparin

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Q13620. Verapamil is used in all, except ?

A.Angina pectoris
B.Atrial fibrillation
C.Ventricular tachycardia
D.None of the above

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Q13622. All drugs are available as transdermal patches in India, except

A.Fentanyl
B.Nitroglycerine
C.Hyoscine
D.Nicotine

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Q13624. Gynaecomastia is caused by which drug ?

A.Spironolactone
B.Rifampicin
C.Thiazide
D.Propanolol

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Q13629. Sedative with GABA facilitating action but without anticonvulsant and muscle relaxant properties and no effect on sleep ?

A.Diazepam
B.Zolpidem
C.Phenobarbitone
D.Buspirone

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