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Questions from standard medical textbooks with detailed explanations

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BiochemistryNucleic Acids
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Q51700.Β In DNA replication the enzyme required in the first step is

A.DNA directed polymerase
B.Unwinding proteins
C.DNA polymerase
D.DNA ligase

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MCQs in BiochemistryNucleic Acids
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Q51701.Β The smallest unit of DNA capable of cod- ing for the synthesis of a polypeptide is

A.Operon
B.Repressor gene
C.Cistron
D.Replicon

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MCQs in BiochemistryNucleic Acids
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Q51702.Β Termination of the synthesis of the RNA molecule is signaled by a sequence in the template strand of the DNA molecule, a signal that is recognized by a termination protein, the

A.Rho (ρ) factor
B.Οƒ factor
C.Ξ΄ factor
D.Ξ΅ factor

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51703.Β After termination of the synthesis of RNA molecule, the core enzymes separate from the DNA template. The core enzymes then recognize a promoter at which the syn- thesis of a new RNA molecule commenc- es, with the assistance of

A.Rho (ρ) factor
B.Ξ΄ factor
C.Ξ² factor
D.Οƒ factor

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51704.Β In the process of transcription in bacterial cells

A.Initiation requires rho protein
B.RNA polymerase incorporates methylated
C.Both the sigma unit and core enzymes of RNA
D.Primase is necessary for initiation

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51705.Β The correct statement concerning RNA and DNA polymerases is

A.RNA polymerase use nucleoside diphosphates
B.RNA polymerase require primers and add
C.DNA polymerases can add nucleotides at both
D.All RNA and DNA polymerases can add

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51706.Β The eukaryotic nuclear chromosomal DNA

A.Is a linear and unbranched molecule
B.Is not associated with a specific membranous
C.Is not replicated semiconservatively
D.Is about of the same size as each prokaryotic

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MCQs in Biochemistry
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Q51707.Β The function of a repressor protein in an operon system is to prevent synthesis by binding to

A.The ribosome
B.A specific region of the operon preventing
C.The RNA polymerase
D.A specific region of the mRNA preventing

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MCQs in Biochemistry
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Q51708.Β All pribnow boxes are variants of the sequence:

A.5′–TATAAT –3β€²
B.5′–GAGCCA –3β€²
C.5′–UAACAA –3β€²
D.5′–TCCTAG –3β€²

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MCQs in BiochemistryNucleic Acids
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Q51709.Β 5’-Terminus of mRNA molecule is capped with

A.Guanosine triphosphate
B.7-Methylguanosine triphophate
C.Adenosine triphosphate
D.Adenosine diphosphate

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MCQs in BiochemistryNucleic Acids
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Q51710.Β The first codon to be translated on mRNA is

A.AUG
B.GGU
C.GGA
D.AAA

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MCQs in BiochemistryNucleic Acids
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Q51711.Β AUG, the only identified codon for methio- nine is important as

A.A releasing factor for peptide chains
B.A chain terminating codon
C.Recognition site on tRNA
D.A chain initiating codon

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MCQs in BiochemistryNucleic Acids
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Q51712.Β In biosynthesis of proteins the chain terminating codons are

A.UAA, UAG and UGA
B.UGG, UGU and AGU
C.AAU, AAG and GAU
D.GCG, GCA and GCU

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MCQs in BiochemistryNucleic Acids
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Q51713.Β The formation of initiation complex during protein synthesis requires a factor:

A.IF-III
B.EF-I
C.EF-II
D.IF-I

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MCQs in BiochemistryNucleic Acids
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Q51714.Β The amino terminal of all polypeptide chain at the time of synthesis in E. coli is tagged to the amino acid residue:

A.Methionine
B.Serine
C.N-formyl methinine(D) N-formal serine

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MCQs in BiochemistryNucleic Acids
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Q51715.Β Initiation of protein synthesis begins with binding of

A.40S ribosomal unit on mRNA
B.60S ribosomal unit
C.Charging of tRNA with specific amino acid
D.Attachment of aminoacyl tRNA on mRNA

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MCQs in Biochemistry
BiochemistryNucleic Acids
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Q51716.Β Initiation of protein synthesis requires

A.ATP
B.AMP
C.GDP
D.GTP

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MCQs in BiochemistryNucleic Acids
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Q51717.Β The enzyme amino acyl tRNA synthetase is involved in

A.Dissociation of discharged tRNA from 80S
B.Charging of tRNA with specific amino acids
C.Termination of protein synthesis
D.Nucleophilic attack on esterified carboxyl

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MCQs in Biochemistry
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Q51718.Β In the process of activation of amino acids for protein synthesis, the number of high energy phosphate bond equivalent utilised is

A.Protein
B.tRNA
C.mRNA
D.rRNA

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MCQs in BiochemistryNucleic Acids
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Q51719.Β In the process of elongation of chain binding of amino acyl tRNA to the A site requires

A.A proper codon recognition
B.GTP
C.EF-II
D.GDP

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MCQs in BiochemistryNucleic Acids
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