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Q55954.Β For healing duodenal ulcer the usual duration of H2 blocker therapy is

A.4 weeks
B.6 weeks
C.8 weeks
D.12 weeks

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Q55955.Β What is true of acid control therapy with H2 blockers ?

A.It generally heals duodenal ulcers faster than
B.It checks bleeding in case of bleeding peptic
C.It prevents gastroesophageal reflux
D.Both (a) and (b)

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Q55956.Β The β€˜acid neutralizing capacity’ of an antacid is governed by

A.The equivalent weight of the antacid
B.The pH of 1N solution of the antacid
C.The rate at which the antacid reacts with HCl
D.Both (a) and (c)

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Q55957.Β An antacid with the following property would be desirable in the treatment of peptic ulcer.

A.Which raises gastric pH to 4.0
B.Which raises gastric pH to 7.0
C.Which increases gastric motility and hastens
D.Both (b) and (c)

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Q55958.Β Antacid combinations of magnesium and aluminium salts are superior to single component preparations because

A.They have rapid as well as sustained acid
B.They are less likely to affect gastric emptying
C.They are less likely to alter bowel movement
D.All of the above

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Q55959.Β In peptic ulcer, antacids are now primarily used for

A.Prompt pain relief
B.Ulcer healing
C.Preventing ulcer relapse
D.Control of bleeding from the ulcer

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Q55960.Β The following is a noncompetitive anta- gonist at the gastric jparietal cell H2 receptor.

A.Cimetidine
B.Loxatidine
C.Roxatidine
D.Rantidine

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Q55961.Β Gynaecomastia can occur as a side effect of

A.Bromocriptine
B.Levodopa
C.Famotidine
D.Cimetidine

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Q55962.Β Which histamine H2 blocker has maximum inhibitory effect on microsomal cytochrome P-450 enzyme ?

A.Cimetidine
B.Ranitidine
C.Roxatidine
D.Famotidine

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Q55963.Β Choose the correct statement about H2 receptor blockers.

A.They are the most efficacious drugs in
B.They cause fastest healing of duodenal ulcers
C.They are the most commonly used drugs for
D.They afford most prompt relief of ulcer pain

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Q55964.Β Ranitidine is mostly given by intravenous infusion for the following indication.

A.Rapid relief of gastric ulcer pain
B.Prophylaxis of gastric erosion in patients with
C.Zollinger Ellison syndrome
D.Reflux oesophagitis

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Q55965.Β Ranitidine differs from cimetidine in the following manner.

A.It is less potent
B.It is shorter acting
C.It does not have antiandrogenic action
D.It produces more CNS side effects

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Q55966.Β Eradication of H pylori along with gastric antisecretory drugs affords the following benefit(s).

A.Faster relief of ulcer pain
B.Faster ulcer healing
C.Reduced chance of ulcer relapse
D.Both (b) and (c)

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Q55967.Β The drugs employed for anti H pylori therapy include the following except

A.Ciprofloxacin
B.Clarithromycin
C.Tinidazole
D.Amoxicillin

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Q55968.Β The following class of gastric antisecretory drug have primary effect on juice volume, with less marked effects on acid and pepsin content, and also reduce gastric motility

A.Histamine H2 blockers
B.Anticholinergics
C.Proton pump inhibitors
D.Prostaglandins

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Q55969.Β The following drug is an inhibitor of gastric mucosal proton pump.

A.Carbenoxolone sodium
B.Sucralfate
C.Famotidine
D.Lansoprazole

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Q55970.Β Omeprazole exerts practically no other action except inhibition of gastric acid secretion because

A.In transforms into the active cationic forms
B.Its active forms have selective affinity for the
C.Its cationic forms are unable to diffuse out
D.All of the above

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Q55971.Β The most efficacious drug for inhibiting round the clock gastric acid output is

A.Omeprazole
B.Cimetidine
C.Pirenzepine
D.Misoprostol

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Q55972.Β The primary mechanism by which prostaglandins promote ulcer healing is

A.Inhibition of gastric secretion
B.Augmentation of bicarbonate buffered mucus
C.Increased bicarbonate secretion in gastric
D.Increased turnover of gastric mucosal cell

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Q55973.Β Which of the following statements is true about misoprostol ?

A.It relieves peptic ulcer pain, but does not
B.It heals nonsteroidal anti-inflammatory drug
C.It produces fewer side effects than H2 blockers
D.It is the most effective drug for preventing

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