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PharmacologyDrugs Used In Endocrine Disorders
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Q55854. Which of the following compounds is incorrectly matched with one of its therapeutic uses?

A.Raloxifene: Advanced breast cancer
B.Metformin: Non-insulin dependent diabetes
C.Finasteride : Benign prostatic hyperplasia
D.Propylthiouracil: Hyperthyroidism

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MCQs in PharmacologyDrugs Used In Endocrine Disorders
PharmacologyDrugs Used In Endocrine Disorders
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Q55855. Metabolic rate of the following organ is not significantly affected by thyroxine

A.Brain
B.Heart
C.Liver
D.Skeletal muscle

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MCQs in PharmacologyDrugs Used In Endocrine Disorders
PharmacologyDrugs Used In Endocrine Disorders
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Q55856. Actions of thyroxine include the following except

A.Rise in blood sugar level
B.Reduction in plasma cholesterol level
C.Fall in plasma free fatty acid level
D.Induction of negative nitrogen balance

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MCQs in Pharmacology
PharmacologyDrugs Used In Endocrine Disorders
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Q55857. Triiodothyronine is preferred over thyroxine in the treatment of

A.Endemic goiter
B.Cretinism
C.Papillary carcinoma of thyroid
D.Myxoedema coma

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MCQs in PharmacologyDrugs Used In Endocrine Disorders
PharmacologyDrugs Used In Endocrine Disorders
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Q55858. Carbimazole acts by inhibiting

A.Iodide trapping
B.Oxidation of iodide
C.Proteolysis of thyroglobulin
D.Synthesis of thyroglobulin protein

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MCQs in PharmacologyDrugs Used In Endocrine Disorders
PharmacologyDrugs Used In Endocrine Disorders
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Q55859. Antithyroid drugs exert the following action.

A.Block the action of thyroxine on peripheral
B.Block the action of thyroxine on pituitary
C.Block the action of TSH on thyroid
D.Inhibit thyroxine synthesis

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MCQs in Pharmacology
PharmacologyDrugs Used In Endocrine Disorders
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Q55860. A 60-year-old male presents with severe hyperthyroidism and multinodular goiter. It was decided to treat him with 131I. The most appropriate course of treatment would be

A.Immediate 131 I dosing with no other drug
B.Propranolol for 1 week followed by 131 I
C.Propranolol + carbimazole till severe
D.Propranolol + Lugol’s iodine for 2 weeks –

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MCQs in Pharmacology
PharmacologyDrugs Used In Endocrine Disorders
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Q55861. The thyroid inhibitor which produces the fastest response is

A.Radioactive iodine
B.Lugol’s iodine
C.Propylthiouracil
D.Lithium carbonate

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MCQs in PharmacologyDrugs Used In Endocrine Disorders
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Q55862. In the treatment of hyperthyroidism, carbimazole has the following advantage over radioactive iodine.

A.cost of treatment is lower
B.It is preferable in uncooperative patient
C.It is better tolerated by the patients
D.Hypothyrodism when in luced is reversible

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MCQs in Pharmacology
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Q55863. Glucose entry into the cells of the following organ/ tissue is highly dependent on the presence of insulin.

A.Brain
B.Liver
C.Adipose tissue
D.Kidney tubules

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MCQs in PharmacologyDrugs Used In Endocrine Disorders
PharmacologyDrugs Used In Endocrine Disorders
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Q55864. Prolonged testosterone therapy can cause

A.Hypertrophy of seminiferous tubules of testes
B.Hypertrophy of interstitial cells of testes
C.Atrophy of interstitial cells of testes
D.Both (a) and (b)

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MCQs in Pharmacology
PharmacologyDrugs Used In Endocrine Disorders
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Q55865. Testosterone therapy started in a boy of 8 years and continued till puberty is likely to

A.Increase adult stature
B.Reduce adult stature
C.Have no effect on adult stature
D.Cause hypertrophy of penis

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MCQs in Pharmacology
PharmacologyDrugs Used In Endocrine Disorders
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Q55866. Which of the following is true of anabolic steroids ?

A.They are testosterone congeners having
B.They are androgens with relatively selective
C.They are suitable for long-term therapy in
D.Both (b) and (c)

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Q55867. Which of the following drugs has potent antiandrogenic and weak progestational activity ?

A.Digoxin
B.Furosemide
C.Enalapril
D.Amrinone

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MCQs in PharmacologyDrugs Used In Endocrine Disorders
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Q55868. Which of the following is a non-steroidal antiandrogen that has been found to be palliative in advanced carcinoma prostate ?

A.Cyproterone acetate
B.Danazol
C.Finasteride
D.Flutamide

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MCQs in Pharmacology
PharmacologyDrugs Used In Endocrine Disorders
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Q55869. Hormones that form lipophilic esters without prior structural modifications include I. Hydrocortisone II. Testosterone III. Progesterone

A.I only is correct
B.III only is correct
C.I and II are correct
D.II and III are correct

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MCQs in Pharmacology
PharmacologyDrugs Used In Endocrine Disorders
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Q55870. Finasteride acts by

A.Blocking testosterone receptors in the prostate
B.Reducing testosterone secretion from testes
C.Reducing LH secretion from pituitary
D.Reducing circulating as well as prostatic

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MCQs in Pharmacology
PharmacologyDrugs Used In Endocrine Disorders
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Q55871. Transdermal estradiol differs from oral estrogen therapy in that it

A.FSH + LH obtained from urine of menstruating
B.LH obtained from urine of pregnant women
C.FSH + LH obtained from urine of menopausal
D.LH obtained from serum of pregnant mare

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Q55872. In which of the following conditions estrogen is not the primary drug but is added to progestin as adjuvant ?

A.Dysfunctional uterine bleeding
B.Menopausal syndrome
C.Osteoporosis
D.Atrophic vaginitis

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Q55873. Addition of a progestin for 10-12 days each month to estrogen replacement therapy in menopausal women is recommended because the progestin

A.Blocks the increased risk of myocardial
B.Blocks the increased risk of endometrial
C.Reverses vulval atrophy occurring in
D.Enhances the metabolic benefits of estrogen

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MCQs in Pharmacology
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Drugs Used In Endocrine Disorders
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Drugs Used In Endocrine Disorders
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Drugs Used In Endocrine Disorders
Drugs Used In Endocrine Disorders
Drugs Used In Endocrine Disorders
Drugs Used In Endocrine Disorders
Drugs Used In Endocrine Disorders
Drugs Used In Endocrine Disorders
Drugs Used In Endocrine Disorders