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PharmacologyDrugs Acting On Autonomous Nervous System
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Q55374. A patient is admitted to the emergency room with orthostatic hypotension and evidence of marked GI bleeding. Which of the following most accurately describes the probable autonomic response to this bleeding? DRUGS ACTING ON AUTONOMOUS NERVOUS SYSTEM 91

A.Slow heart rate, dilated pupils, damp skin
B.Rapid heart rate, dilated pupils, damp skin
C.Slow heart rate, dry skin, increased bowel
D.Rapid heart rate, constricted pupils,

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MCQs in PharmacologyDrugs Acting On Autonomous Nervous System
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Q55375. Drugs that block the α receptor on effector cells at adrenergic nerve endings

A.Antagonize the effects of isoproterenol on
B.Antagonize some of the effects of
C.Antagonize the effects of epinephrine on
D.Cause mydriasis

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MCQs in Pharmacology
PharmacologyDrugs Acting On Autonomous Nervous System
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Q55376. Yohimbine is an antagonist of ______ receptors.

A.α1
B.α2
C.both (a) and (b)
D.None of the above

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MCQs in PharmacologyDrugs Acting On Autonomous Nervous System
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Q55377. Which of the following organs is innervated only by parasympathetic nerves ?

A.Iris muscles
B.Ciliary muscle
C.Sweat glands
D.Splenic capsule

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MCQs in PharmacologyDrugs Acting On Autonomous Nervous System
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Q55378. Muscarinic cholinergic receptors

A.Are located only on parasympathetically
B.Mediate responses by opening an instrinsic
C.Are present on vascular endothelium which
D.Predominate in the autonomic ganglia

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MCQs in Pharmacology
PharmacologyDrugs Acting On Autonomous Nervous System
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Q55379. The cardiac muscarinic receptors

A.Are of the M1 subtype
B.Are of the M2 subtype
C.Are selectively blocked by pirenzepine
D.Function through the PIP2 → IP3/DAG

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Q55380. Atropine does not exert relaxant/ antis- pasmodic effect on the following muscle

A.Intestinal
B.Ureteric
C.Bronchial
D.Layngeal

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MCQs in PharmacologyDrugs Acting On Autonomous Nervous System
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Q55381. α1 – receptors are coupled with _______ G protein.

A.Gs
B.Gi
C.Gq
D.Go

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Q55382. Hyoscine differs from atropine in that it

A.Exerts depressant effects on the CNS at
B.Exerts more potent effects on the heart than
C.Is longer acting
D.Has weaker antimotion sickness activity

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Q55383. Which of the following anticholinergic drugs is primarily used in preanaesthetic medication and during surgery

A.Glycopyrrolate
B.Pipenzolate methyl bromide
C.Isopropamide
D.Dicyclomine

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Q55384. Glycopyrrolate is the preferred antimus- cannic drug for use before and during surgery because

A.It is potent and fast acting
B.It has no central action
C.It has antisecretory and vagolytic actions
D.All of the above

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Q55385. Which of the following mydriatics has the fastest and briefest action ?

A.Atropine
B.Homatropine
C.Tropicamide
D.Cyclopentolate

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Q55386. The most suitable mydratic for a patient of corneal ulcer is

A.Atropine sulfate
B.Homatropine
C.Cyclopentolate
D.Tropicamide

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Q55387. The most effective antidote for belladon- na poisoning is

A.Neostigmine
B.Physostigmine
C.Pilocarpine
D.Methacholine

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Q55388. Atropine is contraindicated in

A.Cyclic AMP
B.Inositol trisphosphate
C.Diacyl glycerols
D.G protein

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Q55389. Select the correct statement from the following about α1 – adrenergic receptor agonists

A.Isoproterenol > epinephrine ≥ norepinephrine
B.Epinephrine > isoproterenol > norepinephrine
C.Isoproterenol = epinephrine ≥ norepinephrine
D.Epinephrine ≥ norepinephrine > isoproterenol

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Q55390. The most efficacious inhibitor of cate- cholamine synthesis in the body is

A.α - methyl – p - tyrosine
B.α - methyldopa
C.α - methyl - norepinephrine
D.Pyrogallol

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Q55391. Tyramine induces release of noradrenaline from adrenergic nerve endings

A.By depolarizing the axonal membrane
B.By mobilizing Ca2+
C.By a nonexocytotic process
D.Only in the presence of MAO inhibitors

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Q55392. Choose the correct statement from the following about α1 – adrenergic receptor agonists

A.Norepinephrine > isoproterenol > epinephrine
B.Norepinephrine < epinephrine > isoproterenol
C.Epinephrine ≥ norepinephrine >> isoproterenol
D.Epinephrine > isoproterenol > norepinephrine

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Q55393. A sympathomimetic amine that acts almost exclusively by releasing noradrenaline from the nerve endings is

A.Ephedrine
B.Dopamine
C.Isoprenaline
D.Tyramine

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