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PharmacologyDrugs Acting On Autonomous Nervous System
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Q55334. Postural hypotension is a common ad- verse effect of which one of the follow- ing types of drugs ?

A.ACE inhibitors
B.Alpha-receptor blockers
C.Arteriolar dilators
D.β1 – selective receptor blockers

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MCQs in PharmacologyDrugs Acting On Autonomous Nervous System
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Q55335. A visitor from another city comes to your office complaining of incessant cough. He has diabetes and hypertension and has recently started taking a different antihypertensive medication. The most likely cause of his cough is

A.Enalapril
B.Losartan
C.Minoxidil
D.Propranolol

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Q55336. Reserprine, an alkaloid derived from the root of Rauwolfia serpentina

A.Can be used to control hyperglycemia
B.Can cause severe depression of mood
C.Can decrease gastrointestinal secretion and
D.Has no cardiac effects

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Q55337. Nitroglycerin, either directly or through reflexes, results in which one of the following effects

A.Decreased heart rate
B.Decreased venous capacitance
C.Increased afterload
D.Increased cardiac force

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Q55338. The antianginal effect of propranolol may be attributed to which one of the following

A.Block of exercise – induced tachycardia
B.Decreased end – diastolic ventricular volume
C.Dilation of consticted coronary vessels
D.Increased cardiac force

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Q55339. The major common determinant of myo- cardial oxygen consumption is

A.Blood volume
B.Cardiac output
C.Diastolic blood pressure
D.Heart rate

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Q55340. Choose the incorrect statement from the following

A.Sympathetic system increases rate of SA node
B.Sympathetic system causes constriction of
C.Sympathetic system causes increased motility
D.Sympathetic system causes constriction of

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Q55341. Denervation super-sensitivity includes

A.Proliferation of receptors
B.Loss of mechanism for transmitter removal
C.Increased post-junctional responsiveness
D.All of the above

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Q55342. Which of the following is approved for the treatment of hemorrhagic stroke ?

A.Amyl nitrite
B.Hydralazine
C.Isosorbide moninitrate
D.Nifedipine

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Q55343. Which of the following drugs used for the treatment of angina by inhalation has a very rapid onset and a brief duration of effect ?

A.Amyl nitrite
B.Hydralazine
C.Isosorbide mononitrate
D.Nifedipine

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Q55344. Which of the following is a vasodilator drug used for hypertension that lacks a direct effect on autonomic receptors but may provoke anginal attacks?

A.Amyl nitrite
B.Hydralazine
C.Isosorbide mononitrate
D.Nifedipine

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Q55345. The biochemical mechanism of action of digitalis is associated with

A.A decrease in calcium uptake by the
B.An increase in ATP synthesis
C.A modification of the actin molecule
D.An increase in systolic intracellular calcium

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Q55346. A patient has been taking digoxin for several years for chronic heart failure is about to receive atropine for another condition. A common effect of digoxin (at therapeutic blood levels) that can be almost entirely blocked by atropine is

A.Decreased appetite
B.Increased atrial contractility
C.Increased PR interval on the ECG
D.Headaches

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Q55347. In a patient given a cardiac glycoside, important effects of the drug on the heart include which of the following?

A.Decreased atrioventricular conduction
B.Decreased ejection time
C.Increased ectopic automaticity
D.Increased ectopic automaticity

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Q55348. Which of the following situations consti- tutes an added risk of digoxin toxicity ?

A.Starting administration of captopril
B.Starting administration of quinidine
C.Hyperkalemia
D.Hypermagnesemia

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Q55349. At rest, the interior of the typical mammalian neuronal axon potential is approximately ________ mV

A.0
B.–70
C.–100
D.–20

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Q55350. Following enzyme is involved in the synthesis of actylcholine

A.Choline acetyl transferase
B.Acetyl cholinesterase
C.Both (a) and (b)
D.None of the above

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Q55351. Which of the following has been shown to prolong life in patient with chronic congestive failure but has a negative inotropic effect on cardiac contractility?

A.Carvedilol
B.Digitoxin
C.Digoxin
D.Dobutamine

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Q55352. Which of the following is the drug of choice in treating suicidal overdose of digitoxin ?

A.Digoxin antibodies
B.Lidocaine
C.Magnesium
D.Potassium

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Q55353. When used as an antiarrhythmic drug, Lidocaine typically

A.Increases action potential duration
B.Increases contractility
C.Increses PR interval
D.Reduces abnormal automaticity

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